{"id":"W2807046580","doi":"10.1177/1759091418777329","title":"In Vivo Optical Imaging of Myelination Events in a Myelin Basic Protein Promoter-Driven Luciferase Transgenic Mouse Model","year":2018,"lang":"en","type":"article","venue":"ASN NEURO","topic":"bioluminescence and chemiluminescence research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovation Cluster (Canada)","funders":"Sanofi","keywords":"Luciferase; Genetically modified mouse; Myelin basic protein; Transgene; In vivo; Optogenetics; Preclinical imaging; Myelin; Cell biology; Neuroscience; Biology; Chemistry; Transfection; Central nervous system; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002077035,0.000146854,0.0001567931,0.0001153902,0.00002337395,0.000006628975,0.0002575364,0.0001176438,0.0000163855],"category_scores_gemma":[0.0001377728,0.000147533,0.00006274302,0.0002137506,0.0001334475,0.00002029514,0.00008248647,0.0001565397,0.000005723027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002040862,"about_ca_system_score_gemma":0.0001139654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003545131,"about_ca_topic_score_gemma":0.0001296824,"domain_scores_codex":[0.9986641,0.0000608248,0.0003112961,0.0004146666,0.0002058089,0.0003432817],"domain_scores_gemma":[0.999455,0.00000909821,0.00005028653,0.0002985809,0.0001162364,0.00007082388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000139285,0.0002349082,0.006890033,0.00004873126,0.000003560304,0.000003941405,0.00007532453,0.00002555496,0.9918156,0.00001260728,0.00006559597,0.0006848841],"study_design_scores_gemma":[0.0007762924,0.0001776988,0.0008650561,0.00005408525,0.000003250826,0.000003104148,0.000022628,0.01360576,0.9842206,0.00005779017,0.0000714366,0.0001423549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979619,0.00002526702,0.0007837187,0.0006226792,0.00002448967,0.0004297028,0.00001165361,0.000006355668,0.0001342164],"genre_scores_gemma":[0.9988002,0.00003783471,0.0004431617,0.0001327233,0.0001029155,0.00006526327,0.00001751732,0.00002278554,0.0003775574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0135802,"threshold_uncertainty_score":0.6016221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141215812024693,"score_gpt":0.28249556580282,"score_spread":0.2683739846003507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}