{"id":"W2807052362","doi":"10.1007/s11606-018-4504-9","title":"Design and Interpretation of Noninferiority Trials","year":2018,"lang":"en","type":"letter","venue":"Journal of General Internal Medicine","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"","keywords":"Medicine; Interpretation (philosophy); MEDLINE; Medical physics; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.2831559,0.001017975,0.003789579,0.002483052,0.002197382,0.006040968,0.00342261,0.02399707,0.004723541],"category_scores_gemma":[0.6756348,0.001799491,0.00191514,0.001908789,0.008458403,0.004360428,0.002133057,0.02853626,0.003121005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004731536,"about_ca_system_score_gemma":0.01058462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009954172,"about_ca_topic_score_gemma":0.001780784,"domain_scores_codex":[0.5505911,0.3943549,0.03103225,0.005140397,0.01716807,0.001713403],"domain_scores_gemma":[0.2409682,0.680306,0.02640348,0.02386613,0.02211901,0.006337173],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0141391,0.0003882411,0.008350318,0.00481194,0.001592394,0.002790044,0.00214159,0.002843993,0.0008000759,0.09698005,0.6393794,0.2257829],"study_design_scores_gemma":[0.02187605,0.001842454,0.006376998,0.006622182,0.001345413,0.004469137,0.0005212292,0.0230431,0.002379769,0.5162612,0.414849,0.0004134619],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.002585334,0.006349466,0.04254289,0.9068421,0.03238464,0.002142435,0.0005097946,0.0001876704,0.006455751],"genre_scores_gemma":[0.06695858,0.004134447,0.1475365,0.6558635,0.1089672,0.01242276,0.0002371211,0.0002377893,0.0036421],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.7168441,"threshold_uncertainty_score":0.8839964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6128194483842326,"score_gpt":0.591942085636786,"score_spread":0.02087736274744667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}