{"id":"W2807081886","doi":"10.1200/jco.2018.36.18_suppl.lba4001","title":"Unicancer GI PRODIGE 24/CCTG PA.6 trial: A multicenter international randomized phase III trial of adjuvant mFOLFIRINOX versus gemcitabine (gem) in patients with resected pancreatic ductal adenocarcinomas.","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":138,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston General Hospital; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Gemcitabine; Internal medicine; Hazard ratio; Clinical endpoint; FOLFIRINOX; Pancreatic cancer; Gastroenterology; Irinotecan; Surgery; Cancer; Randomized controlled trial; Confidence interval; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.007692438,0.0002876905,0.004932273,0.0004970476,0.00004914623,0.00001247737,0.0004599787,0.0004656776,0.0007294987],"category_scores_gemma":[0.02346849,0.0001770415,0.0006290222,0.0003641841,0.00167107,0.0001960935,0.0001511637,0.001368015,0.00001393118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00044888,"about_ca_system_score_gemma":0.003477768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001114428,"about_ca_topic_score_gemma":0.0001791745,"domain_scores_codex":[0.9908483,0.001987626,0.005030557,0.0004133511,0.001217855,0.000502335],"domain_scores_gemma":[0.9860641,0.007461124,0.003343808,0.0004435126,0.002197172,0.0004903155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8457232,0.0120989,0.1338687,0.00002824168,0.002099327,0.0003303783,0.0003061442,9.505904e-7,0.00003010655,0.00002247676,0.0006559859,0.004835592],"study_design_scores_gemma":[0.7984434,0.09580353,0.1023855,0.0002508917,0.001318765,0.00002412623,0.00007969289,0.0004822492,0.00002410609,0.00004713708,0.001013539,0.0001270515],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877546,0.0001851367,0.00008774923,0.002013439,0.003768855,0.003567499,0.00001365954,0.00001130609,0.002597762],"genre_scores_gemma":[0.9940511,0.0004598711,0.00258824,0.0002268608,0.002063585,0.00009008648,0.00002270446,0.00003148857,0.0004660579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08370463,"threshold_uncertainty_score":0.9847572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1264772848552606,"score_gpt":0.4860946307585331,"score_spread":0.3596173459032724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}