{"id":"W2807183470","doi":"10.3390/pathogens7020053","title":"Manipulation of Innate and Adaptive Immunity by Staphylococcal Superantigens","year":2018,"lang":"en","type":"review","venue":"Pathogens","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Superantigen; Biology; Immunology; Toxic shock syndrome; Staphylococcus aureus; Immune system; Immunity; Acquired immune system; Major histocompatibility complex; T-cell receptor; Innate immune system; T cell; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003594466,0.0004825749,0.002051447,0.0002344145,0.0001024862,0.0000155046,0.0001604848,0.000463568,0.00009236384],"category_scores_gemma":[0.0001417017,0.000406861,0.0004430932,0.0003981256,0.0004219705,0.00005263559,0.0001292352,0.0004549692,0.00003771317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001123221,"about_ca_system_score_gemma":0.0002511288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005157477,"about_ca_topic_score_gemma":0.00001652156,"domain_scores_codex":[0.9978108,0.0002197004,0.0008273704,0.0004979504,0.0002790164,0.0003651833],"domain_scores_gemma":[0.9983314,0.0001617141,0.0004510405,0.0005980032,0.0002993815,0.000158418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003572454,0.0005127888,0.0005427554,0.04389756,0.001340627,0.0001887033,0.0007166201,1.728596e-7,0.007941863,0.0005079124,0.006313278,0.9376805],"study_design_scores_gemma":[0.0005484711,0.0004416234,0.0006015803,0.01317858,0.001906292,0.000118853,0.00007893568,0.00001428679,0.0002641368,0.00003596737,0.9822595,0.0005518395],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005083273,0.9907978,0.0003308622,0.000007202997,0.0001288209,0.00130191,0.00124358,0.00004235516,0.001064211],"genre_scores_gemma":[0.00341778,0.9944808,0.001059937,0.00002402471,0.0001350855,0.00003257181,0.0004521707,0.00009305966,0.0003046033],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9759461,"threshold_uncertainty_score":0.9998384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05463217920913304,"score_gpt":0.3250704961937588,"score_spread":0.2704383169846257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}