{"id":"W2807519281","doi":"10.1016/j.jtho.2018.05.030","title":"Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC","year":2018,"lang":"en","type":"review","venue":"Journal of Thoracic Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":662,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Roche","keywords":"Medicine; Liquid biopsy; Anaplastic lymphoma kinase; Lung cancer; Circulating tumor cell; Oncology; Molecular pathology; Biopsy; Molecular diagnostics; Internal medicine; Pathology; Intensive care medicine; Cancer; Medical physics; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000731319,0.0004179354,0.001287899,0.00007030188,0.0001167207,0.00004116529,0.000783406,0.0005624554,0.00007615112],"category_scores_gemma":[0.0001631213,0.0002749277,0.0008378089,0.00009594965,0.0001060528,0.000005805545,0.000251817,0.0003797996,0.000006753688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003399702,"about_ca_system_score_gemma":0.002961135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004011371,"about_ca_topic_score_gemma":0.0001960817,"domain_scores_codex":[0.9976394,0.000199899,0.001190508,0.0004147499,0.0001474778,0.0004079792],"domain_scores_gemma":[0.9964759,0.0003961261,0.002020344,0.0005034576,0.0004397887,0.0001643377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001642405,0.0002694239,0.00001071891,0.00267908,0.001238919,0.00004422365,0.0001804484,0.00003998779,0.003480623,0.000004170184,0.09494867,0.8954613],"study_design_scores_gemma":[0.0005668657,0.002199068,0.000003514425,0.001939216,0.002022989,0.00005316559,0.00007095142,0.000004744627,0.0009918154,0.00002087615,0.9918104,0.0003163599],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003767279,0.9888159,0.002007774,0.0004280787,0.003017912,0.0009832724,0.0007518245,0.000002705184,0.0002252611],"genre_scores_gemma":[0.0001345031,0.9887329,0.004915893,0.0008101968,0.004585919,0.0002131001,0.0001736895,0.00008321457,0.0003505981],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8968617,"threshold_uncertainty_score":0.9999703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02515770169668327,"score_gpt":0.4100484760315295,"score_spread":0.3848907743348462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}