{"id":"W2807614295","doi":"10.1186/s12915-018-0537-0","title":"Proteasomal degradation competes with Mia40-mediated import into mitochondria","year":2018,"lang":"en","type":"letter","venue":"BMC Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Deutsche Forschungsgemeinschaft","keywords":"Intermembrane space; Biology; Mitochondrial intermembrane space; Ubiquitin; Proteasome; Cell biology; Cytosol; Mitochondrion; Proteolysis; Transport protein; Ubiquitin ligase; Biochemistry; Lysine; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001608974,0.0005533865,0.0005371238,0.0001585047,0.0001443358,0.00003092832,0.0004422512,0.002549414,0.0003434372],"category_scores_gemma":[0.0002353583,0.0004370298,0.0001780343,0.0001466743,0.0005370539,0.000004388574,0.0001576816,0.0007456171,0.0003327491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003197843,"about_ca_system_score_gemma":0.0004139763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007416245,"about_ca_topic_score_gemma":0.0004252096,"domain_scores_codex":[0.9971892,0.0004611804,0.0004711253,0.001141868,0.0001495245,0.000587127],"domain_scores_gemma":[0.9983388,0.00007197032,0.0003962534,0.0008339122,0.0002580644,0.000100967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003934112,0.00003211289,0.01006648,0.00007895158,0.000127193,0.00003022941,0.00001655267,6.101052e-7,0.2171417,0.00002711777,0.7719456,0.0001400868],"study_design_scores_gemma":[0.0009811333,0.001883909,0.0002875256,0.00002638698,0.00006720766,0.0002036572,0.00001024166,0.00001182193,0.01467095,0.0001036086,0.9811716,0.0005819344],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.4572452,0.00633847,0.1307329,0.3333028,0.03618885,0.01496517,0.002353874,0.001205022,0.01766773],"genre_scores_gemma":[0.004484747,0.0002980795,0.1026183,0.6480685,0.07129981,0.001840164,0.1333673,0.0005811998,0.03744191],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4527604,"threshold_uncertainty_score":0.9998081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431853534412999,"score_gpt":0.2444960201457576,"score_spread":0.2301774848016276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}