{"id":"W2807707827","doi":"10.1016/j.atherosclerosissup.2018.04.068","title":"Naringenin Supplementation to a Chow Diet Enhances Energy Expenditure and Fatty Acid Oxidation, and Reduces Adiposity in Ldlr-/- Mice with Isocaloric Food Intake","year":2018,"lang":"en","type":"article","venue":"Atherosclerosis Supplements","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"AMPK; Skeletal muscle; Endocrinology; Internal medicine; Beta oxidation; mTORC1; AMP-activated protein kinase; PI3K/AKT/mTOR pathway; Mitochondrial biogenesis; Oxidative phosphorylation; Protein kinase A; Mechanistic target of rapamycin; Medicine; FGF21; Insulin resistance; Chemistry; Kinase; Insulin; Metabolism; Mitochondrion; Biochemistry; Signal transduction; Fibroblast growth factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000255899,0.001001611,0.001120049,0.0009463104,0.0003365137,0.000517918,0.0005525687,0.0006979366,0.002747229],"category_scores_gemma":[0.0002403269,0.000445943,0.0006219065,0.0003779147,0.0009186491,0.0006548436,0.0004321377,0.002122338,0.0005904397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004216678,"about_ca_system_score_gemma":0.0004194158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001234289,"about_ca_topic_score_gemma":0.003148326,"domain_scores_codex":[0.9996614,0.00004658061,0.00004182545,0.00009051234,0.00007179657,0.00008784804],"domain_scores_gemma":[0.9994875,0.00002911605,0.0001513915,0.00006252371,0.00002752394,0.0002418971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005351235,0.0004616697,0.0003130586,0.00005708256,0.00003147337,0.00005508224,0.00002347382,0.00005616725,0.991751,0.00007954151,0.0001171398,0.001703073],"study_design_scores_gemma":[0.0008623608,0.004460774,0.01477223,0.00003820383,0.0002122501,0.0003041375,0.0001843702,0.001394874,0.9746635,0.0002957908,0.002772507,0.00003895366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960102,0.0005863726,0.001145571,0.0003590411,0.000109667,0.00003562897,0.0007645043,0.0002800971,0.000708867],"genre_scores_gemma":[0.9834816,0.00108582,0.004712643,0.0003419838,0.00008938676,0.0002152608,0.001952715,0.0002119475,0.007908727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002747229,"threshold_uncertainty_score":0.00919044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01976383835524185,"score_gpt":0.2701795555139048,"score_spread":0.2504157171586629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}