{"id":"W2807899609","doi":"10.1161/circulationaha.118.034732","title":"Genetic Risk Stratification","year":2018,"lang":"en","type":"review","venue":"Circulation","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Cumberland Pharmaceuticals","keywords":"Medicine; Risk stratification; Evolutionary biology; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001463523,0.001166942,0.001878061,0.001470274,0.0002645282,0.001713685,0.0009387097,0.001561348,0.004121611],"category_scores_gemma":[0.003556823,0.0002952472,0.0007836329,0.001324272,0.0006058173,0.000948192,0.0009141833,0.002856067,0.001376133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005311384,"about_ca_system_score_gemma":0.001676405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001585926,"about_ca_topic_score_gemma":0.002241969,"domain_scores_codex":[0.9994745,0.0001577254,0.00006782998,0.0001294819,0.0001296998,0.00004082972],"domain_scores_gemma":[0.9990762,0.000567904,0.00009373286,0.0000398046,0.0001670046,0.00005531072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001674089,0.00008577433,0.002116149,0.006857391,0.0003881671,0.0003180921,0.00005499508,0.0004595749,0.0004646795,0.008028173,0.06662731,0.9144322],"study_design_scores_gemma":[0.0001182387,0.0001177488,0.005585811,0.01216853,0.001169512,0.002593981,0.0001441547,0.0005598565,0.0004201421,0.02367136,0.9533755,0.0000751866],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002105912,0.9940701,0.0009261046,0.001938358,0.001184789,0.000008497595,0.00007752019,0.00001913533,0.00156481],"genre_scores_gemma":[0.002992076,0.9897342,0.001067822,0.00162619,0.003192009,0.000024135,0.0001982359,0.00000735725,0.001157909],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004121611,"threshold_uncertainty_score":0.0137881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04220575022739401,"score_gpt":0.3260232855930756,"score_spread":0.2838175353656817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}