{"id":"W2807944903","doi":"10.3390/cancers10060205","title":"Oncolytic Reovirus and Immune Checkpoint Inhibition as a Novel Immunotherapeutic Strategy for Breast Cancer","year":2018,"lang":"en","type":"article","venue":"Cancers","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; Calgary Laboratory Services; University of New Brunswick; University of Calgary","funders":"Alberta Innovates","keywords":"Oncolytic virus; Immune system; Immune checkpoint; Cancer research; Breast cancer; Cancer immunotherapy; Immunotherapy; Medicine; Cancer; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002072006,0.0001618858,0.0001459663,0.00004601375,0.0001425479,0.00003813993,0.0001147219,0.000123031,0.0001638869],"category_scores_gemma":[0.00001201666,0.0001586598,0.00007448304,0.0001034514,0.0002801794,0.000006801053,0.00004347451,0.00008150626,0.00001046036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000326686,"about_ca_system_score_gemma":0.000977418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006734897,"about_ca_topic_score_gemma":0.0009376255,"domain_scores_codex":[0.9989688,0.0000250872,0.0001864964,0.0003625716,0.0001173157,0.0003396978],"domain_scores_gemma":[0.9993623,0.000009269145,0.00007634291,0.0002856985,0.000179391,0.00008694822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003681228,0.00001577053,0.00002180621,0.00002643398,0.0001067747,5.317586e-7,0.0000663329,0.00008278184,0.9630742,0.00002966776,0.0001300245,0.03276447],"study_design_scores_gemma":[0.002402568,0.003253783,0.000804081,0.00004813274,0.00002548537,0.00003003938,0.0001057269,0.0004068985,0.9874801,0.0002060184,0.004986819,0.0002503176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941452,0.003557823,0.0004183828,0.0003475453,0.0001505958,0.0005187462,0.0001992714,0.00001540592,0.0006469869],"genre_scores_gemma":[0.9966936,0.0008872643,0.00008976136,0.0006649146,0.0005298574,0.0002463882,0.00003457108,0.00004515421,0.0008084658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03251415,"threshold_uncertainty_score":0.6469959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03031830255682979,"score_gpt":0.3397396547546556,"score_spread":0.3094213521978258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}