{"id":"W2808030315","doi":"10.1016/j.jnutbio.2018.06.001","title":"Betaine or folate can equally furnish remethylation to methionine and increase transmethylation in methionine-restricted neonates","year":2018,"lang":"en","type":"article","venue":"The Journal of Nutritional Biochemistry","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Transmethylation; Betaine; Methionine; Transsulfuration; Homocysteine; Choline; Cysteine; Chemistry; Biochemistry; Methanethiol; Methionine synthase; Cystathionine beta synthase; Internal medicine; Endocrinology; Biology; Amino acid; Sulfur; Enzyme; Medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001979819,0.0002647548,0.0003326797,0.0001940767,0.0000807378,0.0002077169,0.0002767723,0.0003938802,0.0007628924],"category_scores_gemma":[0.0002979636,0.0001640836,0.0002091039,0.00007025622,0.0002295888,0.000223355,0.0002321953,0.0004945094,0.000182877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002126613,"about_ca_system_score_gemma":0.0001978893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006591515,"about_ca_topic_score_gemma":0.001118388,"domain_scores_codex":[0.9998648,0.00004014892,0.00001380572,0.00003599674,0.00002275588,0.00002246204],"domain_scores_gemma":[0.9997328,0.00004939793,0.00008748885,0.00003252535,0.00002562252,0.00007217097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001259913,0.00003233098,0.0009708217,0.00004934769,0.000007940295,0.0001356094,0.00003979647,0.00002686598,0.9951944,0.00003311186,0.00002232427,0.002227464],"study_design_scores_gemma":[0.00007525176,0.005498781,0.0200321,0.00003530409,0.00005229616,0.0007572771,0.0001700661,0.0004111059,0.9697462,0.00008224776,0.003124443,0.00001490397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979538,0.001032262,0.0005010974,0.00004461575,0.000009636235,0.0000114968,0.00009775357,0.00001821167,0.0003310249],"genre_scores_gemma":[0.9937132,0.001099844,0.002357005,0.00007135432,0.00001022914,0.00006373302,0.0002554308,0.00001488891,0.002414366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007628924,"threshold_uncertainty_score":0.002552092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0270772221824321,"score_gpt":0.3268218269946389,"score_spread":0.2997446048122068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}