{"id":"W2808072822","doi":"10.1139/bcb-2017-0310","title":"Post-transcriptional regulation in hematopoiesis: RNA binding proteins take control","year":2018,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Biology; RNA-binding protein; Haematopoiesis; Hematopoietic stem cell; Transcriptional regulation; Cell biology; Stem cell; RNA splicing; Polyadenylation; Translation (biology); RNA; Regulation of gene expression; Translational regulation; Alternative splicing; Post-transcriptional regulation; Gene expression; Computational biology; Gene; Genetics; Messenger RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005048513,0.0007942701,0.0009492171,0.001537604,0.0003625961,0.00114959,0.0008735649,0.001256279,0.003459098],"category_scores_gemma":[0.0006594034,0.0002428301,0.000306679,0.001861274,0.0008784332,0.001670619,0.0008711975,0.001918553,0.00317196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007075709,"about_ca_system_score_gemma":0.001013413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005830556,"about_ca_topic_score_gemma":0.0007574914,"domain_scores_codex":[0.9998208,0.00002501073,0.00002468008,0.00004256242,0.00006700805,0.00002002819],"domain_scores_gemma":[0.9997126,0.0001309071,0.00003576356,0.00001480059,0.00006806961,0.00003779204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006122085,0.00003446663,0.0001749193,0.009502322,0.00004839164,0.0002184993,0.0000930504,0.0003929699,0.003496906,0.01303061,0.02656782,0.9463788],"study_design_scores_gemma":[0.000004211906,0.00003036925,0.000298588,0.0008851072,0.00002171088,0.000678216,0.00003711017,0.00004470036,0.0005308752,0.002793582,0.9946667,0.00000887412],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000921165,0.9977749,0.0002369937,0.0002922338,0.0003361624,0.000002586441,0.00001232369,0.00001050411,0.001242189],"genre_scores_gemma":[0.0009507646,0.9972034,0.0002550153,0.0002229674,0.0002876694,0.000005128912,0.0000256971,0.000003124013,0.001046353],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003459098,"threshold_uncertainty_score":0.01157182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01726231682851054,"score_gpt":0.2816264802782869,"score_spread":0.2643641634497763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}