{"id":"W2808170676","doi":"10.7759/cureus.2798","title":"Dosage Adjustments for Chemotherapy and Targeted Therapies in Colorectal and Pancreatic Cancer Patients with Hepatic Impairment","year":2018,"lang":"en","type":"review","venue":"Cureus","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Medicine; Colorectal cancer; Chemotherapy; Oncology; Pancreatic cancer; Internal medicine; Disease; Metastasis; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005675022,0.0004110317,0.0008700001,0.001262815,0.0001840762,0.000584818,0.0007110483,0.0007814722,0.003101208],"category_scores_gemma":[0.001426592,0.0001526332,0.000707895,0.0008865678,0.0003147499,0.0007348894,0.0003611988,0.001338691,0.0009921055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003593483,"about_ca_system_score_gemma":0.0004927562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006545425,"about_ca_topic_score_gemma":0.001434928,"domain_scores_codex":[0.9995328,0.0001202169,0.0001360384,0.00004257013,0.0001486732,0.00001965488],"domain_scores_gemma":[0.9996365,0.0001920597,0.000104783,0.000008967533,0.00004696761,0.00001078296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001386762,0.00006006464,0.0003876377,0.02177745,0.0001478587,0.0003002991,0.00007807079,0.0002757945,0.001312081,0.002128216,0.02327441,0.9501194],"study_design_scores_gemma":[0.0001018849,0.0002217098,0.003139585,0.01575297,0.0004190627,0.005137106,0.0001170288,0.0002037936,0.00123787,0.001905765,0.9717291,0.00003417908],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004257442,0.9968353,0.0002439805,0.0005143876,0.0001497687,0.00001553848,0.00003838124,0.00001250228,0.001764433],"genre_scores_gemma":[0.004180553,0.9932887,0.001008725,0.0005386515,0.0001871441,0.00003318977,0.0000934435,0.000005098041,0.0006645616],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003101208,"threshold_uncertainty_score":0.01037455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02983158413373464,"score_gpt":0.3630610345646875,"score_spread":0.3332294504309529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}