{"id":"W2808280305","doi":"10.3233/jad-180121","title":"Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation","year":2018,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; McGill University; Douglas Mental Health University Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Nursing Research; National Institute on Aging","keywords":"Deep brain stimulation; Neuromodulation; Fornix; Clinical trial; Medicine; Adverse effect; Stimulation; Randomized controlled trial; Dementia; Physical medicine and rehabilitation; Internal medicine; Disease; Hippocampus; Parkinson's disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005722342,0.00014618,0.0002639807,0.00006810055,0.0002376429,0.00001815943,0.000134226,0.0000388667,0.00003025655],"category_scores_gemma":[0.0009933691,0.00007874912,0.0002979749,0.0001730838,0.00009223104,0.0001785754,0.00004029386,0.000137336,0.000003588707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001321449,"about_ca_system_score_gemma":0.00008385614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009093056,"about_ca_topic_score_gemma":0.000004578782,"domain_scores_codex":[0.9985085,0.0001017129,0.0006562298,0.0001673245,0.0003675696,0.000198636],"domain_scores_gemma":[0.9980493,0.0004456742,0.0007828409,0.0002140179,0.0003679256,0.000140292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8508018,0.003205631,0.01542056,0.00005378672,0.02240253,0.00004980741,0.002182956,0.002148597,0.009802873,0.0006992679,0.03453794,0.05869424],"study_design_scores_gemma":[0.6646471,0.02542974,0.1114244,0.0006856375,0.07170556,0.00001756809,0.001436182,0.03921174,0.03359971,0.03524843,0.01551433,0.001079567],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794199,0.00623948,0.003976016,0.00775821,0.0005160784,0.001907739,0.00002788495,0.00001540247,0.0001392202],"genre_scores_gemma":[0.9968362,0.00002846009,0.001275066,0.001279045,0.0005029445,0.00002439284,0.00002521685,0.00002059158,0.000008124961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1861547,"threshold_uncertainty_score":0.3211296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06103130996917611,"score_gpt":0.3512917437520194,"score_spread":0.2902604337828433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}