{"id":"W2808315477","doi":"10.1002/anie.201804741","title":"Target‐Induced Catalytic Assembly of Y‐Shaped DNA and Its Application for In Situ Imaging of MicroRNAs","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Recruitment Program of Global Experts; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"DNA; In situ; microRNA; Biophysics; In situ hybridization; Computational biology; Cell biology; Biology; Nanotechnology; Molecular biology; Chemistry; Gene; Materials science; Genetics; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002695216,0.0003459918,0.000197195,0.0001552766,0.0001393686,0.0003091732,0.0003012421,0.0005374052,0.0004466122],"category_scores_gemma":[0.0002241499,0.0003284192,0.0002634156,0.0001747915,0.0002953176,0.0002546439,0.0002982762,0.0004306928,0.0003482148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002017465,"about_ca_system_score_gemma":0.0002153141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002903308,"about_ca_topic_score_gemma":0.0003622211,"domain_scores_codex":[0.9998356,0.00003544861,0.000008980976,0.00005005519,0.00004220955,0.00002774161],"domain_scores_gemma":[0.9998987,0.00002296989,0.0000401744,0.00001336583,0.00001279005,0.00001205521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001209669,0.000005586873,0.00003344336,0.00002221117,0.000001963262,0.00003633353,0.00001744577,0.0001007563,0.9981641,0.0002354613,0.00001450451,0.001356049],"study_design_scores_gemma":[0.000002416878,0.0000397906,0.0001012342,0.000001005988,0.000002013594,0.00006291625,0.000004387324,0.0006089925,0.9984725,0.00001838083,0.0006836324,0.00000270138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8704233,0.002783112,0.1210987,0.0001647744,0.00007275474,0.0001120734,0.0001067097,0.0003870972,0.004851556],"genre_scores_gemma":[0.9474787,0.001409263,0.04792909,0.00007929074,0.00001243048,0.0000911861,0.0001014221,0.00005887832,0.00283979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005374052,"threshold_uncertainty_score":0.00149411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01101131417990672,"score_gpt":0.2883350342780427,"score_spread":0.277323720098136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}