{"id":"W2808455819","doi":"10.3389/fcvm.2018.00052","title":"Development of a Contractile Cardiac Fiber From Pluripotent Stem Cell Derived Cardiomyocytes","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cardiovascular Medicine","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Toronto General Hospital","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Science Foundation","keywords":"Contractility; Contraction (grammar); Induced pluripotent stem cell; Fibrin; Stem cell; Beat (acoustics); Connexin; Biomedical engineering; Andrology; Gap junction; Cardiology; Medicine; Biophysics; Internal medicine; Cell biology; Chemistry; Embryonic stem cell; Biology; Immunology; Biochemistry; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002987424,0.0002019455,0.0001558955,0.000146552,0.0001000114,0.0001824825,0.0001068569,0.0003091844,0.0005516359],"category_scores_gemma":[0.000214437,0.0001125718,0.0001829263,0.00009079582,0.0001209817,0.0002287945,0.0002233633,0.000277988,0.0001667114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001078542,"about_ca_system_score_gemma":0.0001399531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001945071,"about_ca_topic_score_gemma":0.0005350133,"domain_scores_codex":[0.999882,0.000009986681,0.00001386205,0.00002151744,0.00005522145,0.0000175294],"domain_scores_gemma":[0.9998808,0.00002238033,0.00003677696,0.000009941505,0.00002195736,0.00002813206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008276614,0.000006228681,0.0003103887,0.00003058152,0.000002381624,0.0000377074,0.00001080959,0.00009273546,0.9971539,0.00004475661,0.00002334363,0.002278895],"study_design_scores_gemma":[0.000009687368,0.0005282814,0.01071053,0.000016994,0.00001715165,0.0004034704,0.00004235281,0.002749806,0.9810581,0.00007750814,0.004378648,0.000007448672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649688,0.001652653,0.03146868,0.00009990582,0.00006592952,0.0001055729,0.0002594956,0.0000849498,0.001294175],"genre_scores_gemma":[0.9590581,0.001472813,0.03676145,0.0001006401,0.0000191571,0.0000980511,0.0005122562,0.00002384813,0.001953557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005516359,"threshold_uncertainty_score":0.001845419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248474774849875,"score_gpt":0.2208958039700072,"score_spread":0.2084110562215085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}