{"id":"W2808480928","doi":"10.1289/ehp2773","title":"Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging","year":2018,"lang":"en","type":"article","venue":"Environmental Health Perspectives","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; Université du Québec à Chicoutimi; McGill University and Génome Québec Innovation Centre","funders":"Fundamental Research Funds for the Central Universities; Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Methylation; DNA methylation; Confidence interval; Urine; Medicine; Physiology; Internal medicine; Biology; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001737863,0.0001302733,0.0001140963,0.00005870358,0.0002152686,0.0000203948,0.00006051431,0.00006557278,0.00001161856],"category_scores_gemma":[0.00002190366,0.0001352945,0.0000269619,0.00006677699,0.0001041678,0.000006424127,0.00006257461,0.00005646368,0.000018921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006908205,"about_ca_system_score_gemma":0.00002217562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004025265,"about_ca_topic_score_gemma":0.000046408,"domain_scores_codex":[0.999028,0.00009714339,0.0001733774,0.0003674426,0.0001109088,0.0002231855],"domain_scores_gemma":[0.9995704,0.00001041485,0.00006918534,0.0001886771,0.000001618727,0.0001597315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002783211,0.00008177548,0.006004076,0.00000450987,0.00002177087,3.46045e-7,0.003939094,0.000003599782,0.9773808,0.00001183916,0.00003868714,0.01248568],"study_design_scores_gemma":[0.0007337288,0.003075232,0.4261086,0.00002758867,0.00001369326,0.000005525685,0.005775752,0.0001104497,0.5583895,0.0005502226,0.004822159,0.0003875472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919701,0.005114594,0.001378579,0.0007721191,0.00006529202,0.0002636909,0.000005641447,0.00001322589,0.0004167726],"genre_scores_gemma":[0.9972333,0.0006743718,0.001292268,0.0002755527,0.0002567545,0.00001671389,0.00003962787,0.00002149975,0.0001899694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4201046,"threshold_uncertainty_score":0.551715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425889009962421,"score_gpt":0.2921917402370959,"score_spread":0.2779328501374717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}