{"id":"W2808639537","doi":"10.1158/1557-3265.hemmal17-45","title":"Abstract 45: BTM-3528 potently induces G1/G0 cell cycle arrest and is efficacious in preclinical models of diffuse large B-cell lymphoma","year":2017,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Paraza Pharma (Canada)","funders":"","keywords":"Cell growth; Cell cycle; Cancer research; Cell cycle checkpoint; Cell culture; Biology; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001898187,0.0007057185,0.0004550992,0.0007379323,0.0002003656,0.0003218551,0.0003643816,0.0004566557,0.003904872],"category_scores_gemma":[0.0001048296,0.0002134963,0.0003269528,0.0003285088,0.0002806874,0.0002583306,0.0001831258,0.00132596,0.0008891447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004288363,"about_ca_system_score_gemma":0.0004253697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001221154,"about_ca_topic_score_gemma":0.002028024,"domain_scores_codex":[0.9998555,0.00002019955,0.000008963512,0.00002172069,0.00004471655,0.00004886308],"domain_scores_gemma":[0.9999012,0.000009016668,0.00001779923,0.000009610714,0.00001295584,0.0000494565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001159054,0.001468276,0.000161116,0.00014794,0.00002882005,0.00006155835,0.00002871873,0.0004852872,0.9885882,0.0002199453,0.0009096155,0.006741479],"study_design_scores_gemma":[0.0008410529,0.02064238,0.005364054,0.00003173232,0.00007244477,0.0003043188,0.00004312176,0.001385035,0.9624304,0.0001443636,0.008725472,0.00001559474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820198,0.00341509,0.002323879,0.0003736498,0.0001365945,0.0004108276,0.002749213,0.0008370004,0.007733923],"genre_scores_gemma":[0.9847339,0.00195723,0.001618435,0.0001437066,0.00002463316,0.000221826,0.002983522,0.00005458396,0.008262187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003904872,"threshold_uncertainty_score":0.01306313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1894158075338028,"score_gpt":0.4809481331695755,"score_spread":0.2915323256357727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}