{"id":"W2808642541","doi":"10.1002/rth2.12117","title":"Pilot trials in thrombosis: Purpose and pitfalls","year":2018,"lang":"en","type":"article","venue":"Research and Practice in Thrombosis and Haemostasis","topic":"Health and Medical Research Impacts","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Thrombosis and Atherosclerosis Research Institute; Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa; Heart and Stroke Foundation of Canada","keywords":"Randomized controlled trial; Medicine; Clinical trial; Consolidated Standards of Reporting Trials; Medical physics; Pilot trial; Rivaroxaban; Research design; Scale (ratio); Physical therapy; Intensive care medicine; Surgery; Warfarin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.7747036,0.00417564,0.01133161,0.008091127,0.004989139,0.01639783,0.0134469,0.0234726,0.004837282],"category_scores_gemma":[0.8167045,0.003956168,0.007207174,0.009630891,0.05616113,0.02992925,0.01228427,0.0406105,0.004835223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01276148,"about_ca_system_score_gemma":0.03205214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003950462,"about_ca_topic_score_gemma":0.004342467,"domain_scores_codex":[0.1620969,0.7190973,0.05834846,0.0123535,0.04663835,0.001465648],"domain_scores_gemma":[0.0607229,0.8411731,0.02379355,0.03446309,0.03535739,0.004490044],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.003273592,0.0004626999,0.005865742,0.04376379,0.002155001,0.0008837878,0.007422496,0.001957638,0.0005236861,0.1775132,0.2330455,0.5231329],"study_design_scores_gemma":[0.004234224,0.002700467,0.004745435,0.1453901,0.001778359,0.003163136,0.003015872,0.006488456,0.001316667,0.4636932,0.3628294,0.0006446088],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.002027679,0.1898703,0.09561452,0.6419271,0.05292318,0.007117767,0.0006703862,0.001057651,0.008791512],"genre_scores_gemma":[0.06058623,0.08629337,0.2121356,0.5652027,0.0510283,0.02065308,0.0003523748,0.0009623983,0.002786037],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.2252964,"threshold_uncertainty_score":0.2778307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6996430230368768,"score_gpt":0.6118585947553993,"score_spread":0.08778442828147748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}