{"id":"W2808653630","doi":"10.1186/s12974-018-1213-6","title":"In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus","year":2018,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Ontario Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Microglia; Biology; Embryonic stem cell; Neuroglia; Cell biology; Pathology; Neuroscience; Central nervous system; Immunology; Medicine; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005115905,0.0001500696,0.0001688306,0.0004318435,0.0001351003,0.0001380804,0.0001806392,0.00007582294,0.00000882045],"category_scores_gemma":[0.0002695388,0.000113874,0.00002536882,0.0002784253,0.00006603096,0.0008089053,0.00003841238,0.0003501582,0.000002569741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003070745,"about_ca_system_score_gemma":0.00005811834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001654585,"about_ca_topic_score_gemma":0.00001173846,"domain_scores_codex":[0.9981644,0.0005788588,0.0005314047,0.0002517953,0.0002835928,0.0001900117],"domain_scores_gemma":[0.9990466,0.0002347954,0.0004984022,0.0001227016,0.00005510125,0.00004246005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006723761,0.00001858507,0.0000633586,0.0000127594,4.15467e-7,0.0001704852,0.0007152812,0.00008163768,0.9972545,0.001124782,0.0001308739,0.0003600742],"study_design_scores_gemma":[0.0006985252,0.0003042222,0.004182274,0.00002535788,0.000004392392,0.0006473818,0.00006398011,0.001240844,0.9910564,0.001478961,0.0001957642,0.0001019188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963628,0.00004187365,0.000569359,0.002456848,0.0002482196,0.0002352738,6.461574e-7,0.000009825971,0.00007517388],"genre_scores_gemma":[0.9978355,0.0002790017,0.000733556,0.0009398676,0.0001639984,0.000004377629,5.825428e-7,0.00001346771,0.00002964063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006198131,"threshold_uncertainty_score":0.4643647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03039993099191143,"score_gpt":0.2703789672425649,"score_spread":0.2399790362506534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}