{"id":"W2808654802","doi":"10.1021/acs.inorgchem.8b00346","title":"Anticancer Activity and Catalytic Potential of Ruthenium(II)–Arene Complexes with N,O-Donor Ligands","year":2018,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Chemistry; Ruthenium; Imine; Moiety; Catalysis; Ligand (biochemistry); Denticity; Amine gas treating; Schiff base; Stereochemistry; Reactive oxygen species; Combinatorial chemistry; Metal; Medicinal chemistry; Biochemistry; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008490609,0.0001653471,0.0003795071,0.0000195247,0.0001094527,0.00001465534,0.00009569486,0.00007212284,0.0005788536],"category_scores_gemma":[0.00004808251,0.0001174931,0.0000454195,0.0001124647,0.0004675024,0.00006587588,0.0001114231,0.0001189435,0.000006848709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000254463,"about_ca_system_score_gemma":0.0001136773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001369966,"about_ca_topic_score_gemma":0.00001039726,"domain_scores_codex":[0.9991466,0.000007353483,0.0001810117,0.0002615054,0.0002131485,0.0001903742],"domain_scores_gemma":[0.99929,0.00002576489,0.0001012773,0.0003495942,0.000127849,0.0001055203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004389468,0.00009742472,0.001787324,0.0003124593,0.0001002934,0.000004355657,0.0001886362,7.654905e-8,0.9962141,0.000006982907,0.00009830968,0.0007510858],"study_design_scores_gemma":[0.0006976613,0.00028796,0.01333527,0.0001464484,0.0001742412,0.0001957581,0.00009426724,0.00007047495,0.9844619,0.00003549879,0.0003570859,0.0001434408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969554,0.0003317628,0.00004651241,0.0003068305,0.00003227075,0.00009669846,0.00001840012,0.00003221455,0.002179919],"genre_scores_gemma":[0.99823,0.0000315316,0.0001988866,0.0000660518,0.0002592396,0.000003617475,0.000008045238,0.00002368704,0.001178967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01175221,"threshold_uncertainty_score":0.6338041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531306755681011,"score_gpt":0.2366492636699375,"score_spread":0.2213361961131274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}