{"id":"W2808926344","doi":"10.1038/s41375-018-0166-1","title":"Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice","year":2018,"lang":"en","type":"article","venue":"Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Deutsche Krebshilfe","keywords":"Myeloid leukemia; Myeloid; Biology; Myeloproliferative Disorders; Cancer research; Leukemia; Gene knockdown; Immunology; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029137,0.0002288257,0.0004084279,0.0003086125,0.00009223093,0.00001710054,0.0002661672,0.000147437,0.0001930856],"category_scores_gemma":[0.0008319214,0.0001880042,0.00009076468,0.0005499304,0.0004424981,0.0001765972,0.0002107946,0.0004453349,0.0001501075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001176739,"about_ca_system_score_gemma":0.002275704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006284069,"about_ca_topic_score_gemma":0.00004981996,"domain_scores_codex":[0.997797,0.00009661434,0.0004589442,0.0005099783,0.0006146154,0.0005228336],"domain_scores_gemma":[0.9985642,0.0001286104,0.0001217965,0.0005338286,0.0003050704,0.0003465256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002597601,0.0001454227,0.01421929,0.000200386,0.00001778283,0.0002649077,0.00200867,0.0000118965,0.9769595,0.0001669298,0.002297133,0.001110488],"study_design_scores_gemma":[0.002892034,0.0003903217,0.1016427,0.0004459919,0.00003856899,0.00002986824,0.0004437056,0.00139511,0.8920045,0.00009746804,0.0004055032,0.0002141908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957426,0.0001646142,0.00009595286,0.0004830484,0.0001094873,0.0006141469,0.00004735836,0.00005693324,0.002685883],"genre_scores_gemma":[0.9962082,0.00004285458,0.001305616,0.0003919084,0.0003206571,0.0000628585,0.00003972855,0.00003815635,0.001590044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08742345,"threshold_uncertainty_score":0.7666589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02630895190364619,"score_gpt":0.3133176343384345,"score_spread":0.2870086824347883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}