{"id":"W2808960992","doi":"10.1186/s13063-018-2718-0","title":"Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): protocol for a prospective randomized controlled trial","year":2018,"lang":"en","type":"article","venue":"Trials","topic":"Intensive Care Unit Cognitive Disorders","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Dexmedetomidine; Medicine; Propofol; Anesthesia; Delirium; Placebo; Sedation; Randomized controlled trial; Acetaminophen; Cardiac surgery; Analgesic; Surgery; Intensive care medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01762517,0.006013916,0.009839593,0.001666768,0.002436741,0.003463987,0.002906356,0.005778033,0.04612867],"category_scores_gemma":[0.02049659,0.002495636,0.004161789,0.002302255,0.003025283,0.002478404,0.001685229,0.005966914,0.006809757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003230221,"about_ca_system_score_gemma":0.009446083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001763798,"about_ca_topic_score_gemma":0.003492334,"domain_scores_codex":[0.9851002,0.009915427,0.001286978,0.001246275,0.001187526,0.001263715],"domain_scores_gemma":[0.9915394,0.002135222,0.002149622,0.001130522,0.001529572,0.001515741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.971508,0.005356127,0.0003917624,0.006106467,0.001130329,0.00008342142,0.00009216068,0.0006119342,0.001004041,0.00101763,0.005422965,0.007275151],"study_design_scores_gemma":[0.9840882,0.009210842,0.0005003681,0.0004635571,0.0003422758,0.00001977845,0.00002260898,0.0005502217,0.0001659221,0.0003802724,0.004227831,0.0000281696],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.00819015,0.0007276715,0.001466778,0.0004520954,0.0007846649,0.984781,0.002100544,0.0001618399,0.001335228],"genre_scores_gemma":[0.007277212,0.0003504048,0.002289446,0.000389144,0.0001653449,0.9882229,0.0003990023,0.00001086331,0.0008957775],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04612867,"threshold_uncertainty_score":0.1543158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07318767119681262,"score_gpt":0.3984774675460599,"score_spread":0.3252897963492473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}