{"id":"W2809112401","doi":"10.1161/atvb.37.suppl_1.348","title":"Abstract 348: Lys 42, 43, 44 and Arg 12 of Thrombin Activable Fibrinolysis Inhibitor Comprise Thrombomodulin Binding Exosite Essential for Exerting Its Antifibrinolytic Activity","year":2017,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Thrombomodulin; Thrombin; Plasmin; Chemistry; Antifibrinolytic; Fibrinolysis; Biochemistry; Molecular biology; Plasminogen activator; Enzyme; Biology; Internal medicine; Endocrinology; Immunology; Medicine; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001426987,0.0006926708,0.0004452613,0.0001352394,0.0001484508,0.0003490773,0.0003371482,0.0004233483,0.003658981],"category_scores_gemma":[0.0002361192,0.0002149334,0.0002708985,0.00015032,0.0003304941,0.0002105618,0.0002806532,0.00059999,0.001653722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002820507,"about_ca_system_score_gemma":0.0002440824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004742135,"about_ca_topic_score_gemma":0.0001612568,"domain_scores_codex":[0.9997715,0.00004794732,0.00002554646,0.00004659942,0.00007237573,0.00003604608],"domain_scores_gemma":[0.999841,0.00002904618,0.00006204376,0.00001539075,0.00001541775,0.00003704477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003700023,0.00004704496,0.0002381838,0.00003837106,0.00001074961,0.0001985753,0.00001323269,0.0001167378,0.9969018,0.0001810944,0.00008942647,0.001795026],"study_design_scores_gemma":[0.00007963905,0.0003940641,0.004717223,0.00000977337,0.00002813315,0.00114296,0.00001518883,0.0009053254,0.9868931,0.0001162212,0.005689666,0.000008722061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903018,0.00110849,0.00518438,0.000245293,0.0001472191,0.00006060009,0.0006273375,0.0001107231,0.002214076],"genre_scores_gemma":[0.9897516,0.000442214,0.003541434,0.00009314992,0.0000446195,0.00004108762,0.001366058,0.00004848392,0.004671381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003658981,"threshold_uncertainty_score":0.01224053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03658825891403759,"score_gpt":0.2973269962729966,"score_spread":0.260738737358959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}