{"id":"W2809123391","doi":"10.1093/humrep/dey221","title":"Peroxiredoxin 6 is the primary antioxidant enzyme for the maintenance of viability and DNA integrity in human spermatozoa","year":2018,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Fondation de l'Hôpital Général de Montréal","keywords":"Antioxidant; Enzyme; Primary (astronomy); Andrology; Biology; DNA damage; DNA; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008760908,0.0001039195,0.0001273541,0.0000202617,0.0002582457,0.000009710503,0.0001651372,0.00009906252,0.0000119105],"category_scores_gemma":[0.0001577809,0.00006100383,0.00005841347,0.00005879663,0.0009512782,0.000005496544,0.00008832438,0.0001215552,5.100783e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001270954,"about_ca_system_score_gemma":0.00001813268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000670114,"about_ca_topic_score_gemma":0.0001795783,"domain_scores_codex":[0.999004,0.0001171023,0.0002258722,0.000453757,0.0000567984,0.0001424555],"domain_scores_gemma":[0.9990857,0.00002180414,0.0001165663,0.0006196743,0.0001421513,0.00001415214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009609431,0.00005357989,0.01082311,0.00003332146,0.00002401367,1.022177e-7,0.0003159301,6.928292e-7,0.9854325,0.0005906223,0.001416888,0.001213149],"study_design_scores_gemma":[0.0002493743,0.000230648,0.2943422,0.00001391144,0.00001101285,0.00001015063,0.0002061805,0.000008172565,0.6946421,0.001187935,0.009024515,0.00007389441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973174,0.0004925063,0.0003147046,0.0009453062,0.0001316591,0.0004542696,0.00001535011,0.0000054467,0.0003233904],"genre_scores_gemma":[0.9987274,0.00007073086,0.00008908645,0.0001120987,0.0004104739,0.00003621118,0.00002251503,0.000007252872,0.0005242082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2907904,"threshold_uncertainty_score":0.3505024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02026451596622028,"score_gpt":0.2889614372475015,"score_spread":0.2686969212812812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}