{"id":"W2809181226","doi":"10.1093/neuonc/noy059.324","title":"IMMU-08. PHASE I TRIAL (NCT02457845) SAFETY, TOLERABILITY AND PRELIMINARY EFFICACY OF IMMUNOVIROTHERAPY WITH HSV G207 IN CHILDREN WITH PROGRESSIVE MALIGNANT SUPRATENTORIAL BRAIN TUMORS","year":2018,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Tolerability; Medicine; Oncology; HSL and HSV; Internal medicine; Adverse effect; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006155345,0.000359628,0.001047393,0.0001638473,0.00009686076,0.00001532606,0.0001332087,0.0001666137,0.0001591201],"category_scores_gemma":[0.0001649334,0.0002299366,0.00009149301,0.0003117874,0.000926676,0.00008752661,0.00007395921,0.0003298907,0.00000524171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001686022,"about_ca_system_score_gemma":0.0006570278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001644314,"about_ca_topic_score_gemma":0.00003244099,"domain_scores_codex":[0.997227,0.0006041072,0.000693875,0.0006898332,0.0003203959,0.0004648508],"domain_scores_gemma":[0.9982101,0.0005346267,0.0003942729,0.0005367621,0.000140284,0.0001839369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.831982,0.01345655,0.06023014,0.00006372609,0.0007184601,0.001084754,0.001546415,0.00000786479,0.03204776,0.0001701169,0.0002355309,0.05845666],"study_design_scores_gemma":[0.4996735,0.3169193,0.1569155,0.0002332128,0.0005297476,0.002526227,0.0002279796,0.00004822624,0.01915477,0.00004140742,0.00333817,0.0003919126],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924924,0.0002861851,0.00003830241,0.002009445,0.0002713731,0.004658757,0.00005451436,0.00003886488,0.0001501251],"genre_scores_gemma":[0.9975422,0.00004718813,0.001023384,0.0004387003,0.0005832187,0.0002167015,0.00008037273,0.0000516698,0.00001655032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3323085,"threshold_uncertainty_score":0.9376542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484198447528479,"score_gpt":0.3184146378266611,"score_spread":0.3035726533513763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}