{"id":"W2809213894","doi":"10.3390/genes9060305","title":"MiRAR—miRNA Activity Reporter for Living Cells","year":2018,"lang":"en","type":"article","venue":"Genes","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; J.P. Bickell Foundation","keywords":"microRNA; Green fluorescent protein; HEK 293 cells; Biology; Reporter gene; Computational biology; Cell biology; Cell culture; Gene expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009880916,0.00007465695,0.00006046206,0.00001525838,0.00006501129,0.00001490813,0.00006783258,0.00007532375,0.00003859375],"category_scores_gemma":[0.00003540339,0.00007342301,0.00006599797,0.00002491344,0.00004217653,0.000002409644,0.0000492904,0.00001064427,0.0000114452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007126529,"about_ca_system_score_gemma":0.0000346957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004901201,"about_ca_topic_score_gemma":0.00002107874,"domain_scores_codex":[0.9994885,0.00001872339,0.00008805968,0.0002223182,0.00004715437,0.0001352635],"domain_scores_gemma":[0.9995376,0.000007793567,0.0000674738,0.0002658418,0.00008180417,0.00003946387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003148838,0.00002149269,0.0008079417,0.00001343056,0.00002113333,3.481673e-7,0.00001629362,0.000002426206,0.9883448,0.00000242339,0.005100685,0.005637572],"study_design_scores_gemma":[0.00009149654,0.00007603312,0.009175327,0.000005986025,0.0000101874,0.000003759074,0.000005003996,0.00007655711,0.9283004,0.00002658701,0.06213464,0.00009397191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913017,0.0002264572,0.007621721,0.00003561369,0.0002494845,0.0001767085,0.00001251205,0.00001201245,0.0003638215],"genre_scores_gemma":[0.996263,0.00001292415,0.001605324,0.00007504209,0.0007816392,0.00002562172,0.00002075623,0.00001569353,0.00119996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06004431,"threshold_uncertainty_score":0.2994103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01413070248888262,"score_gpt":0.2670585725350554,"score_spread":0.2529278700461728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}