{"id":"W2809223047","doi":"10.1016/bs.ircmb.2018.05.010","title":"T Lymphocyte–Based Cancer Immunotherapeutics","year":2018,"lang":"en","type":"review","venue":"International review of cell and molecular biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Oncolytic virus; Chimeric antigen receptor; Biology; Immunotherapy; Cancer immunotherapy; Immune system; Immune checkpoint; Cancer; Cancer research; Antigen; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000331992,0.0002802675,0.001395519,0.0001852815,0.00001555294,0.000006813782,0.0002974303,0.0002424638,0.002981271],"category_scores_gemma":[0.00006600202,0.000200253,0.0005804866,0.0001417649,0.0002391442,0.000009108503,0.00009574228,0.0002049568,0.00003298603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001448848,"about_ca_system_score_gemma":0.0007385578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000219806,"about_ca_topic_score_gemma":7.535034e-7,"domain_scores_codex":[0.9984017,0.0001835659,0.0006256502,0.0003580218,0.000239071,0.0001920038],"domain_scores_gemma":[0.998767,0.0001076455,0.0003575712,0.0003614885,0.0003279708,0.00007828564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003086936,0.00006270788,0.000003008045,0.06830095,0.0004774071,0.00001605385,0.000002480468,9.078173e-9,0.002901771,0.000194617,0.0001862958,0.9278238],"study_design_scores_gemma":[0.0004581397,0.0001862219,4.179436e-7,0.05810971,0.0006132575,0.0000525481,3.614935e-7,0.000005734997,0.001148826,0.00003474491,0.9392457,0.0001443287],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000008071388,0.9913253,0.0002517021,0.0002195728,0.000263862,0.0007590845,0.0000841322,0.000009917622,0.007078343],"genre_scores_gemma":[0.000004375156,0.9950468,0.0004662552,0.002222184,0.0001432179,0.0001300787,0.000359981,0.00004475476,0.001582378],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9390594,"threshold_uncertainty_score":0.9979301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04469470880788873,"score_gpt":0.4333893875353022,"score_spread":0.3886946787274134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}