{"id":"W2809223047","doi":"10.1016/bs.ircmb.2018.05.010","title":"T Lymphocyte–Based Cancer Immunotherapeutics","year":2018,"lang":"en","type":"review","venue":"International review of cell and molecular biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Oncolytic virus; Chimeric antigen receptor; Biology; Immunotherapy; Cancer immunotherapy; Immune system; Immune checkpoint; Cancer; Cancer research; Antigen; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004102578,0.0006077503,0.001016609,0.001329126,0.0001785874,0.0007629407,0.0006683618,0.000785985,0.003251669],"category_scores_gemma":[0.0004876758,0.0001824113,0.0003614083,0.001385507,0.0003947624,0.0009244776,0.000589333,0.001547955,0.001360484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003731863,"about_ca_system_score_gemma":0.0007164829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004526357,"about_ca_topic_score_gemma":0.0009135212,"domain_scores_codex":[0.9998864,0.00002167824,0.00001282523,0.0000223782,0.00003960988,0.00001707398],"domain_scores_gemma":[0.9998466,0.00007209457,0.00002598111,0.0000052088,0.00003565004,0.00001447052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009530134,0.0001117037,0.0001745638,0.01240073,0.00007613077,0.0001636615,0.00003364467,0.0003958355,0.003983425,0.004201093,0.03325542,0.9451085],"study_design_scores_gemma":[0.00003283724,0.0001274156,0.0003683114,0.001524576,0.0001080469,0.0008199789,0.00003364553,0.0001371855,0.001230615,0.001653428,0.9939499,0.00001417664],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002041619,0.9978603,0.0002388201,0.0003636324,0.0003255047,0.000007445601,0.00002062323,0.000009378244,0.0009700684],"genre_scores_gemma":[0.00177886,0.996501,0.0002605051,0.0003632535,0.0002855691,0.00001153189,0.00003365252,0.000001530896,0.0007640441],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003251669,"threshold_uncertainty_score":0.01087791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04469470880788873,"score_gpt":0.4333893875353022,"score_spread":0.3886946787274134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}