{"id":"W2809242708","doi":"10.1007/s11901-018-0407-9","title":"Drug-Induced Liver Injury: Understanding the Different Immune-Mediated Phenotypes and Clinical Management","year":2018,"lang":"en","type":"article","venue":"Current Hepatology Reports","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Alberta Innovates - Health Solutions","keywords":"Phenotype; Liver injury; Immune system; Medicine; Drug; Immunology; Biology; Pharmacology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001932074,0.0003765642,0.0005234313,0.0001669056,0.0009817581,0.00004372724,0.0002392663,0.0004706956,0.00050721],"category_scores_gemma":[0.0001674288,0.0002815806,0.0001775986,0.000264871,0.0009017412,0.0001269309,0.0003431265,0.001525143,0.000154455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001893114,"about_ca_system_score_gemma":0.00007010672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003679322,"about_ca_topic_score_gemma":0.0001391156,"domain_scores_codex":[0.9961935,0.001218641,0.0009988658,0.0007280021,0.0002202232,0.0006407582],"domain_scores_gemma":[0.9980632,0.0005291328,0.0005506484,0.0004989998,0.0001023359,0.0002556741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001048163,0.001733929,0.6985931,0.0003324568,0.001537769,0.0008325531,0.003204715,0.000001056259,0.003235355,0.01346246,0.01395313,0.2620653],"study_design_scores_gemma":[0.006001134,0.001480644,0.1533244,0.0003566858,0.002831666,0.00206391,0.001699032,0.01160584,0.02913,0.03354734,0.7550723,0.002887126],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796843,0.001052535,0.0004102844,0.0008774859,0.01265589,0.001151796,0.00001106274,0.0002029325,0.003953731],"genre_scores_gemma":[0.9965381,0.001784851,0.00002171779,0.0006470394,0.0006429744,0.0001023427,0.00002877001,0.00003136953,0.000202851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7411191,"threshold_uncertainty_score":0.9999636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2213157265772732,"score_gpt":0.4542068309316119,"score_spread":0.2328911043543387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}