{"id":"W2809308879","doi":"10.3390/v10060336","title":"Harnessing T Follicular Helper Cell Responses for HIV Vaccine Development","year":2018,"lang":"en","type":"review","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Germinal center; Immunology; Vaccination; HIV vaccine; Biology; Virology; Antibody; Affinity maturation; B cell; Vaccine trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005074817,0.0006572455,0.0007683911,0.00175079,0.0002144894,0.0007413473,0.0006193063,0.0009510434,0.003783417],"category_scores_gemma":[0.0005311655,0.0002468228,0.0003896544,0.0009845054,0.0003401705,0.00112578,0.0005691664,0.00187015,0.002352661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005503561,"about_ca_system_score_gemma":0.0006928674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000526953,"about_ca_topic_score_gemma":0.001052325,"domain_scores_codex":[0.9998704,0.00001975519,0.00001744118,0.00002383127,0.00005147082,0.00001708036],"domain_scores_gemma":[0.9997861,0.00009561355,0.00003043942,0.000008318207,0.00005271311,0.00002696413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005452196,0.00006282445,0.0001347999,0.00984948,0.00004615011,0.0001363644,0.00003725287,0.0002816574,0.003394419,0.003891822,0.02234332,0.9597674],"study_design_scores_gemma":[0.00001007825,0.00007271753,0.0003560092,0.001575688,0.00004660295,0.0006937269,0.0000249273,0.00005459365,0.0009190393,0.001290871,0.9949457,0.00000997708],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001506069,0.9975763,0.0002653337,0.0003217446,0.0003135726,0.000007898378,0.000020273,0.00001290252,0.00133143],"genre_scores_gemma":[0.0009191813,0.9972988,0.0003658122,0.0002252824,0.0001955005,0.00001171499,0.00003589652,0.000002724179,0.0009450341],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003783417,"threshold_uncertainty_score":0.01265675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08960161079614408,"score_gpt":0.3625838474656765,"score_spread":0.2729822366695324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}