{"id":"W2809308879","doi":"10.3390/v10060336","title":"Harnessing T Follicular Helper Cell Responses for HIV Vaccine Development","year":2018,"lang":"en","type":"review","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Germinal center; Immunology; Vaccination; HIV vaccine; Biology; Virology; Antibody; Affinity maturation; B cell; Vaccine trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003394184,0.0004590917,0.001144759,0.0002707283,0.0004174049,0.00004617064,0.0003384018,0.0004496215,0.0007359591],"category_scores_gemma":[0.0001363797,0.000311261,0.0003513604,0.0001419302,0.00007932544,0.00006403867,0.0001504289,0.0002219106,0.01308717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001431313,"about_ca_system_score_gemma":0.0007856734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001200911,"about_ca_topic_score_gemma":0.000009630275,"domain_scores_codex":[0.9979133,0.0003527535,0.0005141539,0.0005458951,0.00005099563,0.0006229039],"domain_scores_gemma":[0.9986838,0.0005403207,0.0002049597,0.0004301225,0.00008942305,0.00005136147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003228137,0.000447059,0.00003357504,0.007252611,0.001743981,0.00004437741,0.000150359,2.69434e-8,0.0007019187,0.00003100062,0.09270361,0.8965687],"study_design_scores_gemma":[0.0009573222,0.0001550902,0.000005720731,0.002384144,0.0003819305,0.00003355371,0.00001189463,1.591449e-8,0.006102041,0.000003980314,0.9896404,0.0003238809],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001734772,0.9973117,0.0001235091,0.00001635199,0.0003652522,0.001158406,0.0005507729,0.00007897474,0.0002215585],"genre_scores_gemma":[0.00001368467,0.9769155,0.0008831181,0.00007050981,0.0001114211,0.0008167498,0.001448323,0.0000719094,0.01966874],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8969368,"threshold_uncertainty_score":0.999934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08960161079614408,"score_gpt":0.3625838474656765,"score_spread":0.2729822366695324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}