{"id":"W2809322634","doi":"10.1093/neuonc/noy059.262","title":"GERM-15. A PHASE 2 TRIAL OF RESPONSE-BASED RADIATION THERAPY FOR PATIENTS WITH LOCALIZED CENTRAL NERVOUS SYSTEM GERM CELL TUMORS (CNS GCT): A CHILDREN’S ONCOLOGY GROUP (COG) STUDY","year":2018,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Germ cell tumors; Cog; Radiation therapy; Internal medicine; Germinoma; Chemotherapy; Oncology; Germ cell; Progression-free survival; Phases of clinical research; Central nervous system; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005732059,0.0004093737,0.001279843,0.0003593572,0.0001682538,0.00001693652,0.0001821251,0.0002678861,0.00005487822],"category_scores_gemma":[0.0002454101,0.0003012797,0.0002556863,0.0003257458,0.0002294588,0.00005792538,0.00003167662,0.0002055233,0.00001098148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007209124,"about_ca_system_score_gemma":0.0009956801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001458415,"about_ca_topic_score_gemma":0.00009357449,"domain_scores_codex":[0.9959567,0.001341746,0.0009023973,0.0007220209,0.000424262,0.0006529275],"domain_scores_gemma":[0.9964865,0.001435441,0.0008720806,0.0005616458,0.0003302707,0.0003140216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7743565,0.0678134,0.09594835,0.00006838451,0.0005538097,0.0004263309,0.001423168,0.00002019164,0.0148762,0.00002015717,0.00118548,0.04330801],"study_design_scores_gemma":[0.5512014,0.3224747,0.1041158,0.00003764908,0.0009240725,0.0000394202,0.0001907007,0.000404101,0.01062993,0.000002299355,0.009742223,0.0002377104],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985491,0.00008038447,0.0000999944,0.00047237,0.0008907445,0.01263672,0.0001376581,0.0001050961,0.00008602344],"genre_scores_gemma":[0.9963416,0.000010116,0.0002718192,0.0007361182,0.0004877105,0.001882933,0.0001850235,0.00008066006,0.000003977889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2546613,"threshold_uncertainty_score":0.9999439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01549629570990271,"score_gpt":0.3042077213853403,"score_spread":0.2887114256754376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}