{"id":"W2809322634","doi":"10.1093/neuonc/noy059.262","title":"GERM-15. A PHASE 2 TRIAL OF RESPONSE-BASED RADIATION THERAPY FOR PATIENTS WITH LOCALIZED CENTRAL NERVOUS SYSTEM GERM CELL TUMORS (CNS GCT): A CHILDREN’S ONCOLOGY GROUP (COG) STUDY","year":2018,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Germ cell tumors; Cog; Radiation therapy; Internal medicine; Germinoma; Chemotherapy; Oncology; Germ cell; Progression-free survival; Phases of clinical research; Central nervous system; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001949377,0.001150475,0.001131999,0.0003585532,0.0002358842,0.0005925578,0.0008270642,0.0009024956,0.003045971],"category_scores_gemma":[0.0006252558,0.0003938741,0.001110555,0.0002913595,0.0006253705,0.0004765265,0.000391621,0.001590391,0.0005707224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008057393,"about_ca_system_score_gemma":0.001095148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001498236,"about_ca_topic_score_gemma":0.003520965,"domain_scores_codex":[0.9996166,0.0002174081,0.00001438437,0.00005307597,0.000040604,0.00005775666],"domain_scores_gemma":[0.9996601,0.00005410817,0.00007037719,0.00003080454,0.00001715231,0.000167398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7891079,0.04414072,0.01814196,0.001088991,0.001703083,0.0003050909,0.0004157254,0.003831627,0.02129181,0.0006625593,0.007015304,0.1122952],"study_design_scores_gemma":[0.6562836,0.3112065,0.02299878,0.00005347743,0.0005647055,0.0003032504,0.0000611022,0.001418051,0.002214162,0.00025237,0.004623187,0.00002078543],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921194,0.001690934,0.0003049188,0.000300705,0.0000979781,0.0018946,0.001617517,0.00009121092,0.001882765],"genre_scores_gemma":[0.9834061,0.0015977,0.002048424,0.001145291,0.0001126523,0.002977024,0.005185651,0.00003521972,0.003491999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003045971,"threshold_uncertainty_score":0.0103094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01549629570990271,"score_gpt":0.3042077213853403,"score_spread":0.2887114256754376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}