{"id":"W2809326196","doi":"10.1113/jp274705","title":"Compensatory increases in protein markers of mitochondrial dynamics during ageing are adaptable to physical activity","year":2017,"lang":"en","type":"letter","venue":"The Journal of Physiology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"MFN2; Mitophagy; MFN1; Mitochondrion; Cell biology; mitochondrial fusion; Mitochondrial fission; ATP synthase; Electrochemical gradient; DNM1L; Biology; Electron transport chain; Biophysics; Chemistry; Biochemistry; Mitochondrial DNA; Apoptosis; Autophagy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005569014,0.0007666554,0.0008402514,0.001060181,0.0003214727,0.0006310405,0.0003442813,0.0008157895,0.002213461],"category_scores_gemma":[0.0009582106,0.0002616886,0.0005950961,0.0006415536,0.0003409307,0.0005687388,0.0005317463,0.0009763062,0.0008556141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003169224,"about_ca_system_score_gemma":0.0001887048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007164624,"about_ca_topic_score_gemma":0.0008512135,"domain_scores_codex":[0.9995828,0.00005083447,0.00004911307,0.0001469273,0.0001076967,0.00006261638],"domain_scores_gemma":[0.9991747,0.0000643993,0.0003587122,0.00007676968,0.0002115321,0.0001138158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004376634,0.0003708168,0.106979,0.001359612,0.0007700536,0.001777227,0.0007875867,0.0004202892,0.8183327,0.0004658607,0.002864367,0.06149581],"study_design_scores_gemma":[0.00005523786,0.001247098,0.9193174,0.0001447652,0.0003361729,0.002386046,0.000388218,0.0008353632,0.06411085,0.001400666,0.009719352,0.00005883698],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9587481,0.02338271,0.008377822,0.0005589328,0.0003053626,0.0001079721,0.004456773,0.0005151246,0.003547119],"genre_scores_gemma":[0.9852132,0.003926913,0.003097217,0.0003404448,0.000113902,0.0002001808,0.002793123,0.00009809725,0.004216952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002213461,"threshold_uncertainty_score":0.007404745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01290686179256417,"score_gpt":0.248719279616439,"score_spread":0.2358124178238749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}