{"id":"W2809466659","doi":"10.1080/15592294.2018.1461295","title":"DNA methylation analysis from saliva samples for epidemiological studies","year":2018,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Mental Health; National Institutes of Health; DNA Genotek","keywords":"Saliva; Biology; DNA methylation; DNA; Epigenetics; DNA extraction; Methylated DNA immunoprecipitation; Bisulfite sequencing; Methylation; Molecular biology; Polymerase chain reaction; Computational biology; Genetics; Gene; Biochemistry; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006458081,0.0002175067,0.000386122,0.00009368129,0.0001837012,0.00002372501,0.0001946051,0.0002429817,0.00004255261],"category_scores_gemma":[0.001386235,0.0001896215,0.0002764887,0.0002586729,0.000209454,0.000002719299,0.0001109555,0.00005158468,0.00001353732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001962353,"about_ca_system_score_gemma":0.00003291631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000316064,"about_ca_topic_score_gemma":0.0002908108,"domain_scores_codex":[0.9983528,0.000190203,0.0004512958,0.0005633496,0.0001400951,0.0003022369],"domain_scores_gemma":[0.9985098,0.0003138754,0.00019293,0.0004908093,0.0003975753,0.00009496835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001318233,0.00007469785,0.05919484,0.00001308585,0.002036948,4.444721e-7,0.0002681096,0.001226112,0.9192134,0.0004065235,0.001173633,0.01626039],"study_design_scores_gemma":[0.0003963236,0.0007061863,0.08597398,0.000005637314,0.0006523546,1.236443e-7,0.0001260777,0.001025786,0.8394758,0.01359995,0.05769348,0.0003443313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.772257,0.00843285,0.2183409,0.0001884109,0.0002500313,0.0002256571,0.0001319189,0.00001828036,0.0001549298],"genre_scores_gemma":[0.948687,0.002093632,0.04653144,0.0002155976,0.001379933,0.00004493822,0.0008227485,0.00002486793,0.0001998568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.17643,"threshold_uncertainty_score":0.773254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09330015414788057,"score_gpt":0.3780574386645614,"score_spread":0.2847572845166808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}