{"id":"W2809523598","doi":"10.1111/age.12660","title":"Two <i><scp>MC</scp>1R</i> loss‐of‐function alleles in cream‐coloured Australian Cattle Dogs and white Huskies","year":2018,"lang":"en","type":"article","venue":"Animal Genetics","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"University of Bern; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Allele; Biology; Genetics; Coat; Locus (genetics); Genotype; Breed; Single-nucleotide polymorphism; Coding region; Compound heterozygosity; Phenotype; Gene; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001306185,0.0001429412,0.0001376971,0.0000518149,0.00005373393,0.00002389948,0.0001011179,0.0001421417,0.00001836371],"category_scores_gemma":[0.00004099155,0.0001458954,0.00003705526,0.00009513446,0.0001785605,0.000004914171,0.00007129397,0.00006113578,0.000009797834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007962246,"about_ca_system_score_gemma":0.00003459015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007064779,"about_ca_topic_score_gemma":0.0006265835,"domain_scores_codex":[0.999097,0.00005272168,0.0002327318,0.0002830472,0.000115698,0.0002188174],"domain_scores_gemma":[0.999549,0.00001486888,0.00009265947,0.0001818918,0.00009428284,0.00006730916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009266186,0.00008574862,0.1702726,0.00002696642,0.00003696071,0.000002398788,0.000428249,0.00002837827,0.822907,0.0001318768,0.005430249,0.0005569219],"study_design_scores_gemma":[0.001210102,0.002354967,0.3535325,0.00002097805,0.0000449877,0.0000206692,0.0006708134,0.00006714937,0.6207045,0.000246284,0.02098666,0.0001403597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968204,0.0005289697,0.000153566,0.00006407986,0.0001352556,0.0001413588,0.00001734767,0.000007476527,0.002131557],"genre_scores_gemma":[0.9966242,0.0004590562,0.001403671,0.0001377387,0.000286938,0.000009453132,0.0000844913,0.00001877343,0.0009757011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2022025,"threshold_uncertainty_score":0.5949442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0126199759185825,"score_gpt":0.2665134669806814,"score_spread":0.2538934910620989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}