{"id":"W2809843782","doi":"10.2147/itt.s163614","title":"Multiple effects of CD40–CD40L axis in immunity against infection and cancer","year":2018,"lang":"en","type":"review","venue":"ImmunoTargets and Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CTL*; Cytotoxic T cell; Immune system; Immunology; CD8; CD40; Immunity; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006239146,0.0007668459,0.002213548,0.000538837,0.000334356,0.00004067539,0.0003039095,0.0009293787,0.0001524558],"category_scores_gemma":[0.0001578719,0.0005949906,0.0003951926,0.0003655947,0.0007257377,0.0001763534,0.0001662641,0.00087534,0.00003944314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008311121,"about_ca_system_score_gemma":0.0002104237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00222673,"about_ca_topic_score_gemma":0.0001132608,"domain_scores_codex":[0.9965315,0.001273393,0.0009946187,0.0005644379,0.00006178905,0.0005742928],"domain_scores_gemma":[0.9974791,0.001076747,0.0006391988,0.0006738411,0.000104095,0.00002695879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006218727,0.0003072109,0.0006149777,0.003190195,0.001286416,0.00000319926,0.0008825089,1.263293e-7,0.01294449,0.0000136756,0.0000975345,0.9800378],"study_design_scores_gemma":[0.003229928,0.0004612394,0.003456112,0.00623899,0.0001318763,0.00005117297,0.00001247391,3.731248e-7,0.003227167,0.00002758597,0.9825552,0.0006078518],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1637101,0.8337746,0.00000549392,0.000008268294,0.001264637,0.001084269,0.00006037244,0.00004786092,0.00004444153],"genre_scores_gemma":[0.006647162,0.9919088,0.00002548807,0.00005834056,0.00005460386,0.0002779399,0.0002119864,0.00009119339,0.0007244111],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9824577,"threshold_uncertainty_score":0.9996501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02618873157004733,"score_gpt":0.3080459511115065,"score_spread":0.2818572195414591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}