{"id":"W2809843782","doi":"10.2147/itt.s163614","title":"Multiple effects of CD40–CD40L axis in immunity against infection and cancer","year":2018,"lang":"en","type":"review","venue":"ImmunoTargets and Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CTL*; Cytotoxic T cell; Immune system; Immunology; CD8; CD40; Immunity; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002874468,0.0006022273,0.0007547023,0.001349287,0.0002405511,0.000740938,0.0005079064,0.000827893,0.003152383],"category_scores_gemma":[0.0002314663,0.000159826,0.0002874383,0.0009427256,0.0003077994,0.0007788204,0.0004691453,0.001125503,0.001360933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004538244,"about_ca_system_score_gemma":0.000749082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004419878,"about_ca_topic_score_gemma":0.0007477347,"domain_scores_codex":[0.9999052,0.00001304017,0.0000150539,0.00001901322,0.0000338384,0.00001389116],"domain_scores_gemma":[0.9999089,0.0000318835,0.00001610726,0.000003286253,0.00002599051,0.0000138106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001171025,0.00007960796,0.0002285931,0.01393374,0.00007596107,0.000285201,0.00006407846,0.0003720872,0.009316638,0.006400744,0.02069957,0.9484267],"study_design_scores_gemma":[0.00001332017,0.0001151307,0.0007045614,0.001302647,0.00006109348,0.001325603,0.00004408488,0.0001011833,0.00253677,0.001612287,0.9921693,0.000014006],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003732551,0.9969833,0.0001882976,0.0002771868,0.0002409775,0.000006467407,0.00002489937,0.00001137503,0.001894205],"genre_scores_gemma":[0.002711669,0.994992,0.0002654764,0.000191676,0.0001839098,0.0000108649,0.00004853172,0.00000249092,0.001593386],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003152383,"threshold_uncertainty_score":0.01054573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02618873157004733,"score_gpt":0.3080459511115065,"score_spread":0.2818572195414591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}