{"id":"W2809920876","doi":"10.1148/radiol.2018172601","title":"Hypoxia Detection in Infiltrative Astrocytoma: Ferumoxytol-based Quantitative BOLD MRI with Intraoperative and Histologic Validation","year":2018,"lang":"en","type":"article","venue":"Radiology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; University of Toronto","funders":"Brain Tumour Foundation of Canada; Radiological Society of North America","keywords":"Medicine; Oxygenation; Magnetic resonance imaging; Interquartile range; Hypoxia (environmental); Pathology; Oxygen tension; Imaging biomarker; Tumor hypoxia; Radiology; Nuclear medicine; Ferumoxytol; Internal medicine; Oxygen; Radiation therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124326,0.0001589682,0.0003393739,0.000197649,0.00007908476,0.000009285161,0.00002717027,0.0001075106,0.00003765634],"category_scores_gemma":[0.00008646819,0.0001116352,0.00002379729,0.0002134752,0.0003487526,0.00007140746,0.000008412437,0.0001282466,0.00001799012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001881773,"about_ca_system_score_gemma":0.00006263057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009209584,"about_ca_topic_score_gemma":0.0006911815,"domain_scores_codex":[0.9990592,0.000167272,0.0001806115,0.0003193093,0.00007300504,0.0002006081],"domain_scores_gemma":[0.9994334,0.0001830568,0.00008424601,0.0001201829,0.0001140935,0.00006505222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0123071,0.001861708,0.7401202,0.0000922264,0.0006895106,0.001160182,0.006456099,0.0003696856,0.2121076,0.006636839,0.0006183248,0.01758058],"study_design_scores_gemma":[0.007884696,0.02168854,0.6569902,0.00008178806,0.0001465152,0.0007474734,0.0008085096,0.002750882,0.3080994,0.0002003819,0.0003677335,0.000233882],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957286,0.0002566377,0.002260652,0.000743319,0.00006898716,0.0004835538,0.000005522634,0.00003407656,0.0004186098],"genre_scores_gemma":[0.9958141,0.00002447886,0.003722037,0.0002195989,0.00004829707,0.000121224,0.00002867158,0.00001053208,0.00001101913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09599188,"threshold_uncertainty_score":0.4552349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01806962706074016,"score_gpt":0.2762483958632537,"score_spread":0.2581787688025136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}