{"id":"W2809920876","doi":"10.1148/radiol.2018172601","title":"Hypoxia Detection in Infiltrative Astrocytoma: Ferumoxytol-based Quantitative BOLD MRI with Intraoperative and Histologic Validation","year":2018,"lang":"en","type":"article","venue":"Radiology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; University of Toronto","funders":"Brain Tumour Foundation of Canada; Radiological Society of North America","keywords":"Medicine; Oxygenation; Magnetic resonance imaging; Interquartile range; Hypoxia (environmental); Pathology; Oxygen tension; Imaging biomarker; Tumor hypoxia; Radiology; Nuclear medicine; Ferumoxytol; Internal medicine; Oxygen; Radiation therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007695683,0.0003601666,0.0002312585,0.0004652918,0.0001560669,0.0002379593,0.00020094,0.0002301902,0.0004948666],"category_scores_gemma":[0.00120424,0.0001939986,0.0001291183,0.0001768674,0.0002366572,0.0002676565,0.0002380214,0.0001383228,0.0002139377],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000152874,"about_ca_system_score_gemma":0.0001738545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004235285,"about_ca_topic_score_gemma":0.001097817,"domain_scores_codex":[0.99975,0.00007746545,0.0000245532,0.00006298509,0.00006069458,0.00002438586],"domain_scores_gemma":[0.9995048,0.00006653756,0.00020661,0.00005546875,0.0001134785,0.00005315178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002492766,0.0002243553,0.4564571,0.0001527179,0.00008966627,0.0008766165,0.000304443,0.000866814,0.5090764,0.00008037296,0.0001060802,0.02927263],"study_design_scores_gemma":[0.0001242966,0.004312417,0.860239,0.00002582982,0.0001986466,0.00718882,0.0004526855,0.007682186,0.1185542,0.0001140075,0.001073045,0.00003480655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965223,0.0001986243,0.00297131,0.00001008182,0.000003583655,0.0000336151,0.00003744464,0.00001526241,0.0002078795],"genre_scores_gemma":[0.9962531,0.0001050601,0.003340785,0.00001170499,0.000007059456,0.00004377482,0.00008401821,0.000005101274,0.0001493738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007695683,"threshold_uncertainty_score":0.004069924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01806962706074016,"score_gpt":0.2762483958632537,"score_spread":0.2581787688025136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}