{"id":"W2810339633","doi":"10.1158/1538-7445.am2018-4670","title":"Abstract 4670: Evidence of neoantigen-reactive T cell response in a case of relapsing, mismatch-repair gene proficient, colorectal cancer","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; McGill University","funders":"","keywords":"Cancer research; T cell; Metastasis; CD8; Cancer; T-cell receptor; clone (Java method); Colorectal cancer; Biology; Antigen; Immunology; Medicine; Gene; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001658973,0.000447521,0.0004061938,0.001059059,0.0006577436,0.0003748687,0.000328719,0.001185571,0.002181703],"category_scores_gemma":[0.0008840477,0.0002532587,0.0003388529,0.0003261169,0.0004252068,0.0003008271,0.0002681096,0.0007533435,0.0006129182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004540858,"about_ca_system_score_gemma":0.0002033758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002038723,"about_ca_topic_score_gemma":0.001052463,"domain_scores_codex":[0.9998168,0.00001728748,0.00001808704,0.00006320539,0.0000265147,0.00005810483],"domain_scores_gemma":[0.9995078,0.000148146,0.00006819469,0.00004828576,0.00004891713,0.0001786034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.001080803,0.0002070569,0.1020396,0.0001031427,0.00003250119,0.8309863,0.0008660908,0.00037229,0.05846167,0.0002177538,0.0004246612,0.005208082],"study_design_scores_gemma":[0.00006308023,0.001312675,0.1337359,0.00002583561,0.00008064108,0.8456919,0.0003786695,0.003025953,0.01360096,0.0001753206,0.001884307,0.00002475981],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967783,0.0003066222,0.0003320243,0.000150865,0.00002454704,0.00002803362,0.00008621181,0.00003586913,0.002257386],"genre_scores_gemma":[0.9993954,0.00006670455,0.0001486512,0.00005840121,0.00002883266,0.000004389646,0.00004910161,0.000004694989,0.0002438646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002181703,"threshold_uncertainty_score":0.007298529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09864081204970468,"score_gpt":0.4436609745009744,"score_spread":0.3450201624512697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}