{"id":"W2810579527","doi":"10.1016/j.euo.2018.08.009","title":"Modeling 1-year Relapse-free Survival After Neoadjuvant Chemotherapy and Radical Cystectomy in Patients with Clinical T2–4N0M0 Urothelial Bladder Carcinoma: Endpoints for Phase 2 Trials","year":2018,"lang":"en","type":"article","venue":"European Urology Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute","keywords":"Cystectomy; Medicine; Bladder cancer; Perioperative; Oncology; Nomogram; Neoadjuvant therapy; Internal medicine; Stage (stratigraphy); Chemotherapy; Proportional hazards model; Confidence interval; Urology; Clinical trial; Surgery; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0154037,0.002252007,0.002199842,0.0004589046,0.0003477081,0.001496174,0.00193217,0.001608214,0.001799021],"category_scores_gemma":[0.01746301,0.0007556155,0.005677591,0.0004462328,0.0006907666,0.001307735,0.0008719317,0.002050314,0.0002867657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001994509,"about_ca_system_score_gemma":0.002294701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005054178,"about_ca_topic_score_gemma":0.004232112,"domain_scores_codex":[0.9964756,0.002806055,0.00009669561,0.0003681871,0.00009138471,0.0001620326],"domain_scores_gemma":[0.9845436,0.01262895,0.001577201,0.0005539227,0.0003037797,0.0003925983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.06361257,0.004143313,0.09356223,0.0008786233,0.006974528,0.000134016,0.0002639574,0.7847682,0.001067674,0.001492389,0.003808746,0.03929389],"study_design_scores_gemma":[0.006884879,0.0205499,0.0393009,0.0001709093,0.004315612,0.0001442995,0.0001275847,0.9209812,0.001045674,0.004831609,0.001549074,0.00009824363],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877389,0.002817077,0.004598906,0.001076936,0.00008551892,0.0003701642,0.002370518,0.00007714366,0.000864853],"genre_scores_gemma":[0.9914396,0.00054971,0.002811012,0.0002457459,0.00007097171,0.0005656504,0.003280583,0.00003435514,0.001002424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0154037,"threshold_uncertainty_score":0.08146352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04498250182132508,"score_gpt":0.3556424278472148,"score_spread":0.3106599260258898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}