{"id":"W2810804251","doi":"10.1523/eneuro.0174-18.2018","title":"Extending the Time Domain of Neuronal Silencing with Cryptophyte Anion Channelrhodopsins","year":2018,"lang":"en","type":"article","venue":"eNeuro","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; National Institutes of Health; Hermann Eye Fund; Oogfonds; Welch Foundation","keywords":"Optogenetics; Channelrhodopsin; Rhodopsin; Transmembrane domain; Inhibitory postsynaptic potential; Gene silencing; Halorhodopsin; Biophysics; Photostimulation; Neuroscience; Chemistry; Biology; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001450971,0.0002152107,0.0001312251,0.00009341982,0.00006679317,0.0002085651,0.0001640498,0.0001817056,0.0008661303],"category_scores_gemma":[0.0001674007,0.00007934062,0.0002084184,0.00006465852,0.0001424293,0.000203033,0.0001731211,0.0004985242,0.0002130665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002943391,"about_ca_system_score_gemma":0.0001597685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004406356,"about_ca_topic_score_gemma":0.0006210651,"domain_scores_codex":[0.9999157,0.000006304881,0.000009244844,0.00002495332,0.00002838137,0.00001535747],"domain_scores_gemma":[0.9998841,0.00002648241,0.00003877298,0.00001681749,0.0000139744,0.00001983494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002126578,0.000004730719,0.00002437804,0.000008451936,9.779517e-7,0.000005620327,0.000004399492,0.0000408505,0.9992291,0.00007783554,0.000006415372,0.0005760347],"study_design_scores_gemma":[0.000006319197,0.0001107485,0.0009350834,0.000002118942,0.000004031405,0.00004661691,0.000005850252,0.0009863948,0.9964879,0.00004090006,0.001371084,0.000002983591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818721,0.001119711,0.01414111,0.0001291582,0.00003932174,0.00003231978,0.0002206014,0.0001852537,0.00226029],"genre_scores_gemma":[0.9926447,0.0005513971,0.004202622,0.00005596687,0.000007940999,0.00004185517,0.0002262179,0.00003582231,0.002233505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008661303,"threshold_uncertainty_score":0.002897561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02925165784596244,"score_gpt":0.2834371793040589,"score_spread":0.2541855214580965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}