{"id":"W2810973315","doi":"10.1182/bloodadvances.2018019034","title":"Exposure-adjusted adverse events comparing blinatumomab with chemotherapy in advanced acute lymphoblastic leukemia","year":2018,"lang":"en","type":"article","venue":"Blood Advances","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Amgen","keywords":"Blinatumomab; Medicine; Adverse effect; Internal medicine; Incidence (geometry); Cytokine release syndrome; Lymphoblastic Leukemia; Leukemia; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002160498,0.0003166962,0.000860929,0.0002369378,0.0001276518,0.0004415268,0.0003201725,0.0003234852,0.003091258],"category_scores_gemma":[0.003782373,0.0001543914,0.001534613,0.0004594467,0.0001707008,0.0004512936,0.0002303545,0.001140548,0.0002642847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006804911,"about_ca_system_score_gemma":0.0006791652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007915308,"about_ca_topic_score_gemma":0.002267402,"domain_scores_codex":[0.9983023,0.001232968,0.0001048827,0.0001234706,0.0001622111,0.00007416106],"domain_scores_gemma":[0.9977431,0.0009561179,0.0008624718,0.0001300477,0.0001124385,0.0001959227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.793426,0.002853456,0.01985974,0.001625225,0.006852902,0.00008290738,0.0000924128,0.004609723,0.01141528,0.0002938723,0.003035731,0.1558527],"study_design_scores_gemma":[0.2703826,0.4086764,0.2683282,0.0005884953,0.009497591,0.0005199288,0.000167809,0.007283547,0.01259062,0.001567559,0.02030113,0.00009616373],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845356,0.008867367,0.001229061,0.0004853461,0.000143838,0.0005998252,0.00166221,0.00006092278,0.002415703],"genre_scores_gemma":[0.9937477,0.002087937,0.001137318,0.0002811578,0.00009649586,0.0003314368,0.001160542,0.00002065058,0.00113665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003091258,"threshold_uncertainty_score":0.01142597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01216430920173894,"score_gpt":0.279230710711235,"score_spread":0.2670664015094961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}