{"id":"W2810994458","doi":"10.3389/fnmol.2018.00242","title":"Stress Odorant Sensory Response Dysfunction in Drosophila Fragile X Syndrome Mutants","year":2018,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research; University of Pennsylvania; University of Alberta; Vanderbilt University","keywords":"Fragile X syndrome; FMR1; Mutant; Drosophila melanogaster; Intellectual disability; Autism spectrum disorder; Biology; Gene silencing; Neuroscience; Mutation; Genetics; Mushroom bodies; Cell biology; Gene; Autism; Fragile x; Psychology; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002942307,0.0002089105,0.0001671162,0.0002401047,0.00009093008,0.00003853676,0.000377173,0.0001222766,0.000005107407],"category_scores_gemma":[0.0001884618,0.000232494,0.00004187764,0.0004940334,0.0003620085,0.000009965569,0.0001780868,0.0001483396,0.000007488405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003186908,"about_ca_system_score_gemma":0.0001031114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001185698,"about_ca_topic_score_gemma":0.00002065069,"domain_scores_codex":[0.9980179,0.0002114622,0.0002680671,0.000765737,0.0002790733,0.0004577788],"domain_scores_gemma":[0.9993924,0.000005845054,0.00006608876,0.0004059039,0.00003309745,0.0000966308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002795955,0.00009335202,0.01234493,0.000006719821,0.000001999308,0.0002582564,0.00005161113,0.0006933609,0.985458,0.000003736046,0.0003044074,0.0005039907],"study_design_scores_gemma":[0.001251495,0.0009832281,0.4686226,0.00003981785,0.000005434727,0.00009457556,0.0001602004,0.002600705,0.5203477,0.0001852035,0.005176932,0.000532172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931819,0.0001965232,0.004732934,0.0001370869,0.001286667,0.0002516942,0.00002528579,0.00001225491,0.0001756623],"genre_scores_gemma":[0.9972493,0.0001041055,0.001417524,0.000983697,0.00001116597,0.00001850301,0.00001478961,0.00003020822,0.0001707058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4651104,"threshold_uncertainty_score":0.948083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008256427705591814,"score_gpt":0.2263976341950722,"score_spread":0.2181412064894804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}