{"id":"W2811057700","doi":"10.1097/pas.0000000000001114","title":"Molecular Profiling of Hyalinizing Clear Cell Carcinomas Revealed a Subset of Tumors Harboring a Novel EWSR1-CREM Fusion","year":2018,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Salivary Gland Tumors Diagnosis and Treatment","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; St. Paul's Hospital; BC Cancer Agency; University of British Columbia","funders":"","keywords":"Fusion gene; Biology; Gene; Mucoepidermoid carcinoma; Polymerase chain reaction; Stroma; Pathology; Carcinoma; Multiplex polymerase chain reaction; Cancer research; Medicine; Immunohistochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001952784,0.0002851616,0.0001940292,0.0008066345,0.0002430903,0.0003500918,0.0001740036,0.0004209611,0.0006563478],"category_scores_gemma":[0.0006199459,0.0001443958,0.0001722152,0.0002628514,0.0002982404,0.0002153012,0.0002370605,0.0002176552,0.0001839048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000170008,"about_ca_system_score_gemma":0.000148374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005978636,"about_ca_topic_score_gemma":0.0009309638,"domain_scores_codex":[0.999815,0.0000123176,0.00001963135,0.00004368151,0.00006819412,0.00004109576],"domain_scores_gemma":[0.9996507,0.0001028735,0.0000892687,0.00003986564,0.00005457865,0.00006267745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002486329,0.00003724768,0.1297331,0.00004647744,0.00002137182,0.02394154,0.0003245651,0.0002624282,0.8365471,0.0001807243,0.00007235817,0.008584547],"study_design_scores_gemma":[0.00003286896,0.0007034701,0.3987423,0.00001368131,0.0001240643,0.1900011,0.0005810438,0.005882028,0.4004316,0.0004161856,0.003040749,0.00003090906],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980046,0.0001917811,0.001375929,0.00002276819,0.000002089689,0.0000122761,0.00006249039,0.00002205435,0.0003059514],"genre_scores_gemma":[0.9982224,0.00006690418,0.001446764,0.00001234642,0.00000300815,0.000008395118,0.0001020381,0.000004571543,0.0001336211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008066345,"threshold_uncertainty_score":0.002195656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02169663988331454,"score_gpt":0.2808493592378627,"score_spread":0.2591527193545481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}