{"id":"W2811292761","doi":"10.1002/9781119000822.hfcm016","title":"Modeling Therapy of Late or Early‐Stage Metastatic Disease in Mice","year":2017,"lang":"en","type":"other","venue":"Holland‐Frei Cancer Medicine","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; Canada Research Chairs; University of Toronto","funders":"Canadian Cancer Society Research Institute; National Health Research Institutes; National Institute for Health and Care Research; National Institutes of Health; Cancer Research Institute","keywords":"Medicine; Disease; Stage (stratigraphy); Clinical trial; Primary tumor; Oncology; Systemic therapy; Internal medicine; Pathology; Cancer; Metastasis; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000372229,0.0005949048,0.0003219518,0.0007256693,0.0001626954,0.000629371,0.0005077871,0.0004161908,0.004326474],"category_scores_gemma":[0.00009085982,0.0001868472,0.0004228899,0.0003427426,0.0001902723,0.0004721948,0.0003229136,0.0009288843,0.001719916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004188865,"about_ca_system_score_gemma":0.0003907401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005422369,"about_ca_topic_score_gemma":0.001028752,"domain_scores_codex":[0.9999131,0.00001500333,0.00000597116,0.00001449256,0.00003742546,0.00001405686],"domain_scores_gemma":[0.9999539,0.000009381818,0.000009032256,0.000008212355,0.000008182476,0.00001126033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0003526219,0.0003525432,0.0009549553,0.001270365,0.00004782688,0.0002296168,0.0001130292,0.009569285,0.8389487,0.02845203,0.02033767,0.09937148],"study_design_scores_gemma":[0.00006288908,0.0007424083,0.001228283,0.0002664604,0.00009685753,0.00082746,0.00003748331,0.01192879,0.2901458,0.004118298,0.6905093,0.00003594175],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1359729,0.1488235,0.5233188,0.00479302,0.001152306,0.001632542,0.0146377,0.007186645,0.1624827],"genre_scores_gemma":[0.3042939,0.2807291,0.254222,0.001914344,0.0003310939,0.002320714,0.01287854,0.001612011,0.1416984],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004326474,"threshold_uncertainty_score":0.01447344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05413218209413939,"score_gpt":0.3808121866213136,"score_spread":0.3266800045271742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}