{"id":"W2811358329","doi":"10.1016/b978-0-12-813753-6.00008-1","title":"Targeting the Hippo Pathway to Improve Response to Chemotherapy","year":2018,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Hippo signaling pathway; Medicine; Oncology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001027362,0.000377055,0.0002441983,0.000596293,0.0001078505,0.0006282871,0.0002361505,0.0004735127,0.01765004],"category_scores_gemma":[0.0001419905,0.00009110163,0.0001643418,0.0003568692,0.0001362802,0.0004833678,0.0002868363,0.0009775339,0.00741226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003715058,"about_ca_system_score_gemma":0.000182259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003947513,"about_ca_topic_score_gemma":0.001385489,"domain_scores_codex":[0.9999583,0.00000361148,0.000001794275,0.000006599918,0.00002438197,0.000005288829],"domain_scores_gemma":[0.9999762,0.000008844281,0.000003292573,0.000001496007,0.000005436969,0.000004721631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001081798,0.0000938034,0.0001897973,0.0005420988,0.00001828154,0.0001640765,0.00005278505,0.0007040913,0.03226095,0.009827461,0.09851916,0.8575193],"study_design_scores_gemma":[0.00003043721,0.000105021,0.001129027,0.0002585875,0.00001945035,0.0008953791,0.00002370312,0.0006708232,0.01543396,0.005996767,0.9754234,0.00001337511],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.01604179,0.5236507,0.01687199,0.01312369,0.003569508,0.00007807089,0.0008759856,0.001079636,0.4247087],"genre_scores_gemma":[0.07679618,0.3345976,0.009790502,0.003891282,0.00164079,0.00008798214,0.0008366289,0.0003426082,0.5720164],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01765004,"threshold_uncertainty_score":0.05904526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009255354008931276,"score_gpt":0.2356080396366161,"score_spread":0.2263526856276849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}