{"id":"W2811408287","doi":"10.1016/j.freeradbiomed.2018.06.040","title":"Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury","year":2018,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council; National Institutes of Health; Medical Research Council Canada; Wellcome Trust","keywords":"Oxidative stress; Neuroprotection; Reactive oxygen species; Reperfusion injury; Mitochondrion; Ischemia; Mitochondrial ROS; Pharmacology; Hypoxia (environmental); Superoxide; Oxidative phosphorylation; Chemistry; Biology; Cell biology; Oxygen; Biochemistry; Medicine; Internal medicine; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000289161,0.000141842,0.0002747807,0.00007190038,0.00005778222,0.000001389375,0.0001469066,0.0003340917,0.0002672409],"category_scores_gemma":[0.001417242,0.000115192,0.00003055166,0.0001090069,0.001311365,0.000004098275,0.0001026807,0.0001589859,0.000005091543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007137466,"about_ca_system_score_gemma":0.00003396855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005827444,"about_ca_topic_score_gemma":0.0000476233,"domain_scores_codex":[0.9988093,0.0002122856,0.0003369303,0.0003592396,0.00006841278,0.0002138791],"domain_scores_gemma":[0.9994202,0.00009282168,0.0001175569,0.0002118944,0.00006188545,0.00009566659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005380774,0.00002029463,0.002083274,0.000007112712,0.0000144158,0.000001362,0.0001222899,8.002825e-8,0.8676397,0.0004365183,0.1270897,0.002047142],"study_design_scores_gemma":[0.005462862,0.004412353,0.00176623,0.00005220405,0.00002717302,0.00003082225,0.0002200404,0.00007375912,0.5443208,0.001021477,0.4423348,0.0002774494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811264,0.001112662,0.01300988,0.002833062,0.0007363728,0.0002244387,0.0001129184,0.00001068105,0.0008336354],"genre_scores_gemma":[0.9867564,0.0002128884,0.005530187,0.002679406,0.002555749,0.00002076923,0.001764912,0.00001770342,0.000461993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3233189,"threshold_uncertainty_score":0.4831779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01340487216661093,"score_gpt":0.2909525880692954,"score_spread":0.2775477159026845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}