{"id":"W2811427482","doi":"10.1093/infdis/jiy329","title":"Efficacy of Ebola Glycoprotein-Specific Equine Polyclonal Antibody Product Against Lethal Ebola Virus Infection in Guinea Pigs","year":2018,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Emergent BioSolutions (Canada); University of Manitoba; Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Public Health Agency of Canada","keywords":"Ebola virus; Polyclonal antibodies; Virology; Antibody; Ebolavirus; Glycoprotein; Filoviridae; Biology; Guinea pig; Immunology; Medicine; Virus; Viral disease; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003051586,0.0003527778,0.0002679573,0.000204005,0.00008559975,0.0001917925,0.0002917539,0.0004247561,0.0009119709],"category_scores_gemma":[0.0002063595,0.00008795861,0.0002341916,0.00006333952,0.0001758685,0.0001918247,0.0001296721,0.000538172,0.0001760633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001694582,"about_ca_system_score_gemma":0.0001479447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003237542,"about_ca_topic_score_gemma":0.0004620577,"domain_scores_codex":[0.999887,0.00002834115,0.000008213255,0.0000190173,0.00002514531,0.00003224223],"domain_scores_gemma":[0.9998878,0.00002443031,0.00002777695,0.000010185,0.00002400204,0.00002583645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008574887,0.0009652823,0.0006872243,0.0001121372,0.00002742726,0.00007958078,0.00003629868,0.0001950011,0.9892625,0.00007325273,0.00009958381,0.007604109],"study_design_scores_gemma":[0.0002689105,0.03472317,0.01257639,0.00004501611,0.0001113106,0.0005206187,0.00005552771,0.0008010569,0.9479913,0.00004767371,0.002851397,0.000007657333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973667,0.0007835153,0.000785311,0.00004578556,0.00002584958,0.00005336335,0.00007196117,0.00002444536,0.0008432199],"genre_scores_gemma":[0.9970275,0.0006041437,0.0009905867,0.00007008864,0.0000195154,0.00004524654,0.0002535753,0.00000535869,0.0009840151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009119709,"threshold_uncertainty_score":0.003050864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02167149130834888,"score_gpt":0.3354239178901867,"score_spread":0.3137524265818378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}