{"id":"W2811478915","doi":"10.1128/iai.00403-18","title":"Secreted Phosphatase and Deoxyribonuclease Are Required by Pseudomonas aeruginosa To Defend against Neutrophil Extracellular Traps","year":2018,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Athabasca University; University of Calgary","funders":"Canadian Institutes of Health Research; Cystic Fibrosis Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Neutrophil extracellular traps; Biology; Innate immune system; Microbiology; Extracellular; Pseudomonas aeruginosa; Chromatin; Deoxyribonuclease; Immune system; Antimicrobial; Cell biology; Immunity; Inflammation; Bacteria; Immunology; Enzyme; DNA; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002124804,0.0004502877,0.0003178132,0.0002422363,0.0002171784,0.0007448168,0.0002763094,0.0005874889,0.002422201],"category_scores_gemma":[0.0006013394,0.0003180317,0.0004201389,0.0001384553,0.0003006519,0.0005961674,0.0004562383,0.0008588416,0.001202251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003966416,"about_ca_system_score_gemma":0.0003398145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004549166,"about_ca_topic_score_gemma":0.0005748807,"domain_scores_codex":[0.9996786,0.00004574191,0.00003003847,0.00004816123,0.0001084443,0.00008897897],"domain_scores_gemma":[0.9996803,0.00006437061,0.00008149135,0.00005034729,0.00004054046,0.00008297429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001557895,0.00003370727,0.0005018532,0.00003023856,0.000004077933,0.0001614691,0.00001144357,0.00005511792,0.9969695,0.000159692,0.0001081653,0.001808928],"study_design_scores_gemma":[0.00004834818,0.0003800712,0.0291903,0.00001344677,0.000018778,0.001897336,0.0001339141,0.002830331,0.9584168,0.0004534453,0.006594929,0.00002232494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832258,0.005646621,0.00699194,0.0007328921,0.0001262583,0.00004459106,0.0006378306,0.0002214166,0.002372669],"genre_scores_gemma":[0.988061,0.001328924,0.003398651,0.0001582797,0.00003617015,0.00005497357,0.001622199,0.00005398133,0.005285892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002422201,"threshold_uncertainty_score":0.008103132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399829165359833,"score_gpt":0.2319979409735601,"score_spread":0.2179996493199617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}