{"id":"W2832965455","doi":"10.1101/365460","title":"FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University Health Centre; Montreal Clinical Research Institute; Université de Sherbrooke; McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Jewish General Hospital","keywords":"Effector; Homologous recombination; DNA; DNA repair; Biology; Cell biology; Immunoglobulin class switching; DNA damage; Molecular biology; Genetics; Antibody; B cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002528609,0.0003457392,0.0003005,0.0003420297,0.0002064945,0.0004957464,0.0004285419,0.0004592363,0.001794687],"category_scores_gemma":[0.0002041097,0.0001855185,0.0003307365,0.0001299413,0.0002774082,0.0002714583,0.000411361,0.0005037537,0.001122971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006053132,"about_ca_system_score_gemma":0.0001730091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005220208,"about_ca_topic_score_gemma":0.0007787933,"domain_scores_codex":[0.9996676,0.00004469954,0.00002848862,0.0001201817,0.00008485807,0.00005417451],"domain_scores_gemma":[0.9997945,0.00003359765,0.00006375348,0.0000315512,0.00002074941,0.00005586036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005318129,0.00000573543,0.0003288715,0.00001291772,0.000005002712,0.00005546316,0.000004308184,0.00004066627,0.9986618,0.00008937041,0.00004973449,0.000693027],"study_design_scores_gemma":[0.00001131055,0.00007964416,0.005355145,0.000004876931,0.00001138338,0.0004066497,0.00001618719,0.002650812,0.9882439,0.00007009021,0.003143542,0.000006375615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876226,0.001817609,0.007924278,0.000187231,0.00005027002,0.00002375702,0.0005976969,0.0004408483,0.001335711],"genre_scores_gemma":[0.9944279,0.000201776,0.003220001,0.000064082,0.000007998423,0.00001505743,0.000570718,0.00005889553,0.001433594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001794687,"threshold_uncertainty_score":0.006003857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01111321794540826,"score_gpt":0.2290980115914662,"score_spread":0.217984793646058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}