{"id":"W2834442344","doi":"10.1016/j.bbmt.2018.06.035","title":"A Prospective Trial of Extracorporeal Photopheresis for Chronic Graft-versus-Host Disease Reveals Significant Disease Response and No Association with Frequency of Regulatory T Cells","year":2018,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals; Therakos; Vanderbilt University","keywords":"Medicine; Extracorporeal Photopheresis; Internal medicine; Photopheresis; Graft-versus-host disease; Prednisone; Prospective cohort study; Logistic regression; Disease; Clinical trial; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005065727,0.000151114,0.0003940416,0.0001087763,0.00004526683,0.000002837014,0.00003836612,0.0001279117,0.00001515242],"category_scores_gemma":[0.00009445496,0.0001264544,0.00007189419,0.00009228086,0.0003315678,0.00006286906,0.000002614211,0.00005195105,3.638695e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003099587,"about_ca_system_score_gemma":0.0002841167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004250109,"about_ca_topic_score_gemma":0.00002272356,"domain_scores_codex":[0.9987529,0.0001619902,0.0004612619,0.0002943495,0.0001705362,0.0001589586],"domain_scores_gemma":[0.9984257,0.0005646017,0.0004220824,0.0001456156,0.0003041228,0.0001378419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.2305123,0.0002218146,0.05154457,0.001878846,0.0002150793,0.000005993749,0.0003934876,2.68658e-7,0.7148756,0.0002868403,0.000008828321,0.00005636005],"study_design_scores_gemma":[0.07433859,0.009563854,0.3818206,0.0007374032,0.003623782,0.000006245038,0.00006527111,0.00002752474,0.5292248,0.0003973652,0.000006468886,0.0001881968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963011,0.0002540899,0.0005301443,0.000071235,0.000113652,0.001750154,0.0008946138,0.00001467851,0.00007040426],"genre_scores_gemma":[0.9976541,0.0004887339,0.001442246,0.000009373969,0.00008727572,0.00009917131,0.0001517357,0.0000157031,0.00005165362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.330276,"threshold_uncertainty_score":0.5156659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01057634891503783,"score_gpt":0.2498015449918992,"score_spread":0.2392251960768613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}