{"id":"W2836414657","doi":"10.1016/j.omtm.2018.06.009","title":"UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of British Columbia; Institute for Research in Immunology and Cancer; BC Cancer Agency","funders":"BC Cancer Agency; Terry Fox Foundation; Stem Cell Network","keywords":"Gene transfer; Haematopoiesis; Gene; Biology; Virology; Cell biology; Stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003315573,0.0003374619,0.0005458443,0.00009508435,0.0001528854,0.00003210004,0.0004012971,0.0003126592,0.0001074543],"category_scores_gemma":[0.00009438604,0.000305768,0.0002599206,0.0001712226,0.0006695127,0.000007544739,0.0001578041,0.0002262899,0.00001527503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002116957,"about_ca_system_score_gemma":0.0002690491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005169286,"about_ca_topic_score_gemma":0.00001802011,"domain_scores_codex":[0.9958996,0.00152398,0.0009292478,0.0008310413,0.0003492663,0.0004669312],"domain_scores_gemma":[0.9987248,0.0001299809,0.0001361485,0.0005722505,0.0002506888,0.0001861649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001419331,0.0002429364,0.0001511267,0.00001881134,0.0003967036,0.00000528657,0.0002145178,9.072818e-7,0.849957,0.00002629123,0.00002979281,0.1475373],"study_design_scores_gemma":[0.001493665,0.004940673,0.001773038,0.00003083626,0.00001995616,0.000004003509,0.00003493029,0.000004065656,0.9838826,0.0004894556,0.006965824,0.0003609491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8969436,0.002114017,0.09983082,0.00006752396,0.0002014827,0.0004836324,0.000006931282,0.00001524471,0.0003367712],"genre_scores_gemma":[0.8128847,0.002384864,0.1829319,0.0009448777,0.0001823869,0.00008003217,0.00004377688,0.0000785481,0.0004688886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1471763,"threshold_uncertainty_score":0.9999394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0666723510200596,"score_gpt":0.433455202140979,"score_spread":0.3667828511209195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}