{"id":"W2836414657","doi":"10.1016/j.omtm.2018.06.009","title":"UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells","year":2018,"lang":"en","type":"article","venue":"Molecular Therapy — Methods & Clinical Development","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of British Columbia; Institute for Research in Immunology and Cancer; BC Cancer Agency","funders":"BC Cancer Agency; Terry Fox Foundation; Stem Cell Network","keywords":"Gene transfer; Haematopoiesis; Gene; Biology; Virology; Cell biology; Stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002436453,0.0004401174,0.0002321028,0.0003389513,0.0001186832,0.0002715789,0.0001685092,0.0001694712,0.001175169],"category_scores_gemma":[0.000142454,0.0001173353,0.0002528539,0.0001555366,0.0001481982,0.0001238803,0.0003093244,0.0003723578,0.0003022715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001916991,"about_ca_system_score_gemma":0.0002564907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004166257,"about_ca_topic_score_gemma":0.0005828742,"domain_scores_codex":[0.9998362,0.00004509993,0.00001525757,0.00001647408,0.00004522298,0.0000417767],"domain_scores_gemma":[0.9999,0.00002899542,0.00002553215,0.000009405052,0.000009648842,0.00002641685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006184052,0.00002619281,0.0001168781,0.0000336484,0.000003241605,0.00003193633,0.00001425004,0.0001055897,0.9976877,0.00008685701,0.00002787594,0.001804029],"study_design_scores_gemma":[0.000003793735,0.0001605229,0.000525858,0.000004626339,0.000005719694,0.00007751395,0.000007563091,0.0002364618,0.9977357,0.0000124418,0.001228482,0.000001334895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917378,0.001992555,0.003568591,0.00007101323,0.00001478571,0.00004845647,0.0002707011,0.00008286578,0.002213296],"genre_scores_gemma":[0.9902227,0.002069207,0.003693313,0.00005980854,0.00001332455,0.00004981816,0.0006984618,0.00003728167,0.003155972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001175169,"threshold_uncertainty_score":0.003931344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0666723510200596,"score_gpt":0.433455202140979,"score_spread":0.3667828511209195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}