{"id":"W2837980584","doi":"10.1128/jvi.00811-18","title":"Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection","year":2018,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"Canadian Institutes of Health Research; National Institute of Allergy and Infectious Diseases; Poliomyelitis Research Foundation; South African Medical Research Council; Wellcome Trust; Gilead Sciences; Michael Smith Health Research BC; International AIDS Vaccine Initiative","keywords":"Biology; Virology; Human immunodeficiency virus (HIV); Disease; Viral replication; Virus; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002449555,0.0002075813,0.0001811358,0.0001694103,0.0001325744,0.0003624624,0.0001247496,0.0002768235,0.0007967831],"category_scores_gemma":[0.0003784636,0.00009673627,0.0001135223,0.0001207406,0.000182389,0.0001811353,0.00009762013,0.0004953785,0.00009902385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002830259,"about_ca_system_score_gemma":0.0002272862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001530545,"about_ca_topic_score_gemma":0.001560294,"domain_scores_codex":[0.999877,0.00002845667,0.00001012149,0.00001683012,0.00002996031,0.0000376557],"domain_scores_gemma":[0.9997576,0.00009625223,0.0000462596,0.00002063092,0.00002331542,0.00005592663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000521734,0.0002249333,0.005711575,0.00003046281,0.00001245338,0.00005813939,0.00004050574,0.000356294,0.9890694,0.00006741355,0.00005895018,0.003848117],"study_design_scores_gemma":[0.00007822154,0.006818374,0.1814748,0.00003212276,0.00008641853,0.001112282,0.000156537,0.005953288,0.8029233,0.0002289995,0.001110801,0.00002477293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991987,0.0003016978,0.00009182734,0.00001534257,0.000002609464,0.000007347521,0.00006434997,0.000008496566,0.0003095897],"genre_scores_gemma":[0.9993215,0.0001577229,0.0001529675,0.00001826958,0.000002300328,0.000004926155,0.00009551782,0.000003860169,0.0002430421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001530545,"threshold_uncertainty_score":0.003043234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02113075902221071,"score_gpt":0.3211319378420852,"score_spread":0.3000011788198745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}